This new volume of Current Topics in Developmental Biology covers Stem Cells in Development and Disease. The chapters provide a comprehensive set of reviews covering such topics as the mechanisms of pluripotency in vivo and in vitro, hematopoietic stem cell development, intestinal stem cells and their defining niche, epithelial stem cells in adult skin, the mammary stem cell hierarchy, satellite cells, neural stem cells of the hippocampus, lung stem and progenitor cells in tissue homeostasis and disease, spermatogonial stem cell functions in physiological and pathological conditions, the origin, biology, and therapeutic potential of facultative adult hepatic progenitor cells, nephron progenitor cells, adult stem cell niches, cancer stem cells, pluripotency and cellular heterogeneity, and cellular mechanisms of somatic stem cell aging
Rezensionen / Stimmen
"...contains especially strong content on adult stem cells, as well as additional chapters that focus on the more universal themes of pluripotency itself, cancer stem cells, and aging of resident adult stem cell populations." --The Quarterly Review of Biology
Reihe
Sprache
Verlagsort
Verlagsgruppe
Elsevier Science Publishing Co Inc
Zielgruppe
Für höhere Schule und Studium
Für Beruf und Forschung
Researchers in cell, developmental, and molecular biology; genetics
Maße
Höhe: 229 mm
Breite: 152 mm
Gewicht
ISBN-13
978-0-12-416022-4 (9780124160224)
Copyright in bibliographic data and cover images is held by Nielsen Book Services Limited or by the publishers or by their respective licensors: all rights reserved.
Schweitzer Klassifikation
Herausgeber*in
Black Family Stem Cell Institute, Department of Developmental and Regenerative Biology; Icahn School of Medicine at Mount Sinai, NY, USA
1. Mechanisms of Pluripotency In Vivo and In Vitro
2. Hematopoietic Stem Cell Development: An Epigenetic Journey
3. Intestinal Stem Cells and their Defining Niche
4. Epithelial Stem Cells in Adult Skin
5. The Mammary Stem Cell Hierarchy
6. Satellite Cells: The Architects of Skeletal Muscle
7. Neural Stem Cells of the Hippocampus: Development, Physiology Regulation and Dysfunction in Disease
8. Lung Stem and Progenitor Cells in Tissue Homeostasis and Disease
9. Spermatogonial Stem Cell Functions in Physiological and Pathological Conditions
10. The Origin, Biology, and Therapeutic Potential of Facultative Adult Hepatic Progenitor Cells
11. Nephron Progenitor Cells: Shifting the Balance of Self-Renewal and Differentiation
12. Adult Stem Cell Niches: Cellular and Molecular Components
13. Cancer Stem Cells, Pluripotency, and Cellular Heterogeneity: A WNTer Perspective
14. Cellular Mechanisms of Somatic Stem Cell Aging