Viral infections of the central nervous system or neurotropic viruses are often lethal. These diseases range from polio and measles, to rabies, Varicella-zoster, Herpes, West Nile, Japanese encephalitis, and AIDS. Such infections have profound public health consequences, and the understanding of these diseases involves understanding the interaction between the nervous system and the immune system. This book shows each individual virus, discussing the diseases they cause and the mechanisms by which they cause and spread those diseases. Detection, treatment and prevention are also discussed. Included is coverage of novel and beneficial uses of neurotropic viruses for gene therapy and tumor lysis. Neurotropic Viral Infection has been written in a style suitable for a wide professional audience, and will appeal to anyone from graduate students and postdocs to clinicians and public health professionals.
Rezensionen / Stimmen
'The chapter authors and book editors have collaborated to produce a treatise that reads as if written by a single author. Obvious care has been taken throughout the chapters to make the text approachable and understandable by those with limited knowledge of virology and yet with the depth necessary to satisfy the most demanding of scholars.' Michael Goldblatt, President and CEO, Functional Genetics, Inc. 'The authors did an amazing job walking that fine line between too much detail for non-specialists and not enough sophistication for the cognoscenti.' Richard M. Ranshoff, Director, Neuroinflammation Research Center 'I can't imagine a better place to learn than this very well-thought out and comprehensive volume by leading authorities on this important subject.' Stephen S. Morse, Founding Director, Center for Public Health Preparedness, NCDP 'No other book is currently available that has the depth and range of the material presented..... This book will undoubtedly be an important resource to the scientific and medical community.' Etty (Tika) Benveniste, Associate Director, Basic Science Research, Comprehensive Cancer Center, Comprehensive Cancer Center, University of Alabama, Birmingham 'Authoritative, accessible, and extensive ... a must read for any one interested in neurotropic viruses and how to combat them.' Alice S. Huang, Senior Faculty Associate in Biology, California Institute of Technology '... comprehensive, well illustrated and very readable. ... I highly recommend it to all those interested in viruses and neurological disease.' Microbiology Today
Sprache
Verlagsort
Zielgruppe
Illustrationen
28 Tables, unspecified; 12 Plates, color; 21 Halftones, unspecified; 43 Line drawings, unspecified
Maße
Höhe: 257 mm
Breite: 194 mm
Dicke: 27 mm
Gewicht
ISBN-13
978-0-521-86964-5 (9780521869645)
Copyright in bibliographic data and cover images is held by Nielsen Book Services Limited or by the publishers or by their respective licensors: all rights reserved.
Schweitzer Klassifikation
Carol Shoskes Reiss is a professor in the Department of Biology at New York University. She was editor-in-chief of Viral Immunology from 1999-2006.
Herausgeber*in
New York University
Preface. Howard Lipton; Forward and acknowledgments Carol Shoshkes Reiss; Part I. RNA Viruses: Introduction Carol Shoshkes Reiss; 1. Neurotropic picornaviruses Vincent Racaniello; 2. Subacute sclerosing panencephalitis James Bale and Robert S. Fujinami; 3. Rabies Monique Lafon; 4. Neurotropic coronavirus infections Stanley Perlman and Noah Butler; 5. Arenavirus infection in the nervous system: uncovering principles of virus-host interaction and viral pathogenesis Stefan Kunz and Juan-Carlos de la Torre; 6. Neurotropic alphaviruses Diane E. Griffin; 7. Flaviviruses Barbara W. Johnson; Part II. Retroviruses, DNA Viruses and Prions: Introduction Carol Shoshkes Reiss; 8. HTLV-1 and disease in the central nervous system Angelina J. Mosley and Charles R. M. Bangham; 9. HIV infection of the central nervous system Iain C. Anthony P Simmonds and J. E. Bell; 10. JC virus molecular biology and the human demyelinating disease, progressive multifocal leukoencephalopathy Kamel Khalili, Mahmut Safak, Luis Del Valle and Martyn K. White; 11. Herpes simplex viruses David C. Bloom and Nicole V. Giordani; 12. Pathogenesis of varicella-zoster virus neurotropism and infection Leigh Zerboni and Ann M. Arvin; 13. Transmissible spongiform encephalopathies Surachai Supattapone and Judy R. Rees; Part III. Immunity, Diagnosis, Vectors and Beneficial Uses of Neurotropic Viruses: Introduction Carol Shoshkes Reiss; 14. Innate immunity in the CNS Carol Shoshkes Reiss; 15. The role of toll like receptors in neurotropic viral infections Robert W. Finberg, Shenghua Zhou and Evelyn A. Kurt-Jones; 16. Neuro-endocrine-immune networks in viral infections C. Jane Welsh, Andrew J. Steelman, Amy N. Sieve, Wentao Mi, Robin R. Johnson, Colin R. Young, Thomas W. Prentice and Mary W. Meagher; 17. Epidemiology of viral encephalitis Nino Khetsuriani and Larry J. Anderson; 18. Pathogen surveillance and discovery W. Ian Lipkin and Thomas Briese; 19. Clinical management of viral encephalitis Kenneth L. Tyler and Don Gilden; 20. Influences of arthropod vectors on encephalitic arboviruses Stephen T. Higgs; 21. The role of bats as reservoir hosts of emerging neurological viruses John S. Mackenzie, James E. Childs, Hume E. Field, Lin-Fa Wang and Andrew C. Breed; 22. Viral oncolysis of glioblastoma William T. Curry, Jr. and Robert L. Martuza; 23. Viral gene therapy for central nervous system disorders Pedro R. Lowenstein, Kurt M. Kroeger and Maria G. Castro.
