About the Esteve Foundation. Introduction. List of participants. All papers include a Discussion. Pharmacology of exercise. Doping in sport: the extent of the problem (D.R. Mottram, T. Reilly, N. Chester). Testing for drug abuse (D.A. Cowan). Limits to research on drugs and sport (P.M. Clarkson, H.S. Thompson). Health-related issues: use of drugs and exercise (M.H. Williams). Overtraining immunosuppression, exercise-induced muscle damage and anti-inflammatory drugs (M. Gleeson, A.K. Blannin, N.P. Walsh). Health-related aspects of drug abuse and use. Health-related aspects of the use and abuse of beta-adrenoceptor blocking drugs (M. Orme). Sports, free radicals and antioxidants. Methodological considerations (O.I. Aruoma). Nicotine effects during physical activity (K.A. Perkins). Oestrogen, exercise and bone: hormone replacement therapy and oral contraceptives (A.D. Martin, M.A. Petit). Exogenous oestrogen: the female, cardiovascular disease and exercise (K. Birch). Ergogenic aids - short term performance. Physiology of muscle fatigue during intense exercise (J. Bangsbo). Anabolic-androgenic steroids: ergogenic and cardiovascular effects (N.T. Cable). Pharmacology of bodybuilding (T.D. Fahey). Alkalinizers: influence of blood acid-base status on performance (D.P.M. MacLaren). Creatine supplementation in humans (P.D. Balsom). Ergogenic aids - endurance performance. The effect of athletic training and dietary factors on the modulation of muscle glycogen (F. Brouns). Blood doping, erythropoietin and altitude (B. Ekblom). Branched-chain amino acids and endurance performance (A.J.M. Wagenmakers). The human eccrine sweat gland: a possible growth hormone target organ? (A. Juul et al. ). The use of beverages as ergogenic aids (J.B. Leiper). Psychomotor performance. Do psychological strategies for performance enhancement actually work? (K. Davids). The possible actions of methylxanthines on various tissues (T.E. Graham). The role of tranquillisers in sport and exercise (A. Miles). Alcohol: its influence in sport and exercise (T. Reilly). Pharmacology and the travelling athlete (G. Atkinson et al).