Section I.- 1 Signals in the Regulation of Mast Cell Growth and Development: A Perspective.- 2 The Regulation of Mast Cell and Basophil Development by the Kit Ligand, SCF, and IL-3.- 3 The c-kit Receptor and the mi Transcription Factor: Two Important Molecules for Mast Cell Development.- 4 Mouse and Rat Models of Mast Cell Development.- 5 Factors That Affect Human Mast Cell and Basophil Growth.- 6 Signal Transduction by Cytokines.- 7 Mast Cell Apoptosis and Its Regulation.- Section II.- 8 Early Signals in Mast Cell Activation: A Perspective.- 9 Fc?RI Signaling in Specialized Membrane Domains.- 10 Regulation and Function of Protein Tyrosine Kinase Syk in Fc?RI-Mediated Signaling.- 11 The Role of Protein Phosphatases in Cell Signaling by the High-Affinity Receptor for Immunoglobulin E.- 12 Protein Kinase C and Early Mast Cell Signals.- 13 Mast Cell Inhibitory Receptors of the Immunoglobulin Superfamily.- Section III.- 14 Signaling Pathways That Regulate Effector Function: Perspectives.- 15 Phosphoinositide-Derived Second Messengers in Fc?RI Signaling: PI-3 Kinase Products Control Membrane Topography and the Translocation and Activation of PLC-?1 in Antigen-Stimulated Mast Cells.- 16 Phospholipase D and Its Role in Mast Cells.- 17 New Perspectives on Ca2+ Influx in Mast Cells.- 18 The MAP Kinases and Their Role in Mast Cells and Basophils.- 19 Tec Family Protein Tyrosine Kinases and Their Interaction with Protein Kinase ?.- 20 Activation of Heterotrimeric GTP-Binding Proteins.- 21 Activation of Small GTP-Binding Proteins.- Section IV.- 22 Regulation of Mediator Synthesis and Secretion: Overview.- 23 Early-Response Genes in Mast Cell Activation.- 24 Fc?RI-Mediated Activation of NF-AT.- 25 Regulation of IL-4 Expression in Mast Cells.- 26 Arachidonic Acid Metabolism inMast Cells.- 27 Role of ICRAC in the Regulation of Secretion.- 28 Regulation of Secretion in Human Basophils.- 29 Histamine Releasing Factors.
