This ninth volume in the series, comprises twenty-five chapters written by outstanding experts at the forefront of their respective fields. Various aspects of the structure elucidation, synthesis, biosynthesis and biological properties of natural products from diverse marine, fungal, bacterial, amphibian and insect sources, as well as lower and higher plants are described. Physical techniques such as NMR and mass spectral methods are emphasized, and advances in enzyme-substrate interactions are also featured. The scope of information given in this book amply testifies to the enormous potential for the future development of natural products from the marine and terrestrial environments to provide the key biological agents for the future benefit of mankind from renewable resources.
Reihe
Sprache
Verlagsort
Verlagsgruppe
Elsevier Science & Technology
Zielgruppe
Für höhere Schule und Studium
Für Beruf und Forschung
Maße
ISBN-13
978-0-444-89165-5 (9780444891655)
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Schweitzer Klassifikation
Preface (G.A. Cordell). X-Ray crystallographic studies on novel natural products from marine animals (M.I. Choudhary and J.C. Clardy). Marine norterpene cyclic peroxides: a stereochemical paper chase (R.J. Capon). Structure and biosynthesis of cyclopropane-containing sterols of marine origin (C. Djerassi and G.A. Doss). New natural products from terrestrial plants and marine organisms (V.U. Ahmad et al.). NMR in the elucidation of complex structures. Application to two novel heptanortriterpenoid derivatives from the stem bark of Entandrophragma utile ( Meliaceae ) (D.S. Rycroft). NMR of chalcogen nuclei and their application in natural products chemistry (H. Duddeck). Principles and applications of modern 2D NMR techniques in structure elucidation of complex natural products (Atta-ur-Rahman et al.). Rapid identification of trace amounts of indole alkaloids: Analysis of the aromatic pattern from the 1 H-NMR spectrum (J. Schripsema and R. Verpoorte). The Fusarium genus: A versatile biosynthetic engine (J.W. ApSimon et al.). Chemistry of self-inhibitors of fungal spore germination (T. Ueno et al.). Structural elucidation of some natural products (J.D. Connolly). Isolation and structural studies of constituents of Euphorbia fidjiana (R.C. Cambie et al.). Isolation and structure elucidation of new cytotoxic agents from Nerium oleander and chemical constituents of Azadirachta indica with reference to their biological activity (S. Siddiqui et al.). The chemistry of non-isoprenoid phenolic lipids (J.H.P. Tyman). "Bench-top" bioassays for the discovery of bioactive natural products: an update (J.L. McLaughlin et al.). Some advances in the research of corticoid hormones (R. Vlahov et al.). Bio-organic chemistry of ansamycin and mitomycin antibiotics (R.W. Rickards). Chromatographic and mass spectrometric methods for the analysis of the steryl esters of plants (R.P. Evershed and L.J. Goad). Tandem mass spectrometry ( FABMS/MS ) studies of peptides and proteins (K.L. Rinehart et al.). New results in phosphaheterocyclic chemistry and total synthesis of 25-oxa-25-phospha-vitamin D 3 - the first phosphorus analog of vitamin D 3 (R. Neidlein). Comparative studies of various Artemisia oils (P. Weyerstahl et al.). Peptide siderophores from bacteria (H. Budzikiewicz). Substrates and products of lipoxygenase catalysis (G.A. Veldink and J.F.G. Vliegenthart). Mechanistic and evolutionary aspects of vitamin B 12 biosynthesis (A.I. Scott). Subject Index.
