Synthesis of natural products containing five-membered rings. An evolution of general methodology (T. Hudlicky et al.). Synthetic studies on natural products possessing eight- or nine-membered rings (T. Oishi, Y. Ohtsuka). Total synthesis of polyquinane terpenes (S. Ito et al.). New synthetic methodology. The trityl salts catalyzed stereoselective Michael reaction leading to natural products (T. Mukaiyama, S. Kobayashi). New methodology for the synthesis of biologically active lactones (C.W. Jefford et al.). The aureolic acid antitumor antibiotics: a challenge for organic synthesis (R.W. Franck, S.M. Weinreb). Recent developments in modern synthetic carbohydrate chemistry (Z.J. Witczak). Recent applications of sigmatropic reactions to the synthesis of highly-oxygenated natural products (J. Kallmerten, M.D. Wittman). A formal total synthesis of colchicine (E. Wemkert, H.-S. Kim). Natural and synthetic antitumor agents: synthetic studies on CC-1065 and functionally related agents (R.S. Coleman, D.L. Boger). Recent advances on the synthesis of quinolone skeleton by [4+2] cycloaddition reaction and its application to the natural products synthesis (T. Kametani, H. Kasai). Synthesis of yohimbine and related alkaloids (I. Ninomiya, O. Miyata). Synthesis of natural products via arynes (L. Castedo, E. Guitian). Synthesis of Erythrina alkaloids (Y. Tsuda, T. Sano). The structures, reactions and syntheses of arteannuin (Qinghaosu) and related compounds (W.-S. Zhou, X.-X. Xu). Subject Index.