Myocardial hibernation is a clinical entity characterized by the combination of chronic hypocontractility, hypoperfusion, viability of the myocardium and reversibility of dysfunction post-evascularization. This text presents a study which includes: discussion of the development of the experimental animal model; surgical induction of chronic coronary artery stenosis in sheep; and an evaluation of the experimental animal model and the effects of revascularization on the hibernating myocardium.
Sprache
Verlagsort
Zielgruppe
Für höhere Schule und Studium
Für Beruf und Forschung
Maße
ISBN-13
978-90-6186-911-5 (9789061869115)
Copyright in bibliographic data is held by Nielsen Book Services Limited or its licensors: all rights reserved.
Schweitzer Klassifikation
Part 1 Development of the experimental animal model: sheep as an experimental animal; regional myocardial blood flow in sheep. Part 2 Surgical induction of chronic coronary artery stenosis in sheep: anaesthesia; surgery. Part 3 Evaluation of the experimental animal model: experimental protocol; global and regional myocardial function. Part 4 The effects of revascularization on the hibernating myocardium: percutaneous transluminal coronary angioplasty (PTCA) - experimental model, experimental protocol and methods; transmyocardial revascularization (TMR) -experimental model, experimental protocol and methods. Part 5 General discussion.
