The Biological Basis of Drug Tolerance and Dependence

A book intended for research workers, graduate/third year undergraduate students in neuroscience and pharmacology and interested research clinicians. This volume provides comprehensive reviews of the cellular and molecular mechanisms underlying tolerance to, and dependence upon, a wide spectrum of psychotropic drugs of abuse. The common neuroanatomical pathways involved, and the adaptive processes that occur at the receptor level, are discussed, together with how such features relate to the clinical problem. This is the third in the "Neurosciences Perspectives" and in common with the aims of the series provides up-to-date reviews of its topical subject from the biochemical and pharmacological points of view, with the historical perspective and prospects for clinical application.
 
A book intended for research workers, graduate/third year undergraduate students in neuroscience and pharmacology and interested research clinicians. This volume provides comprehensive reviews of the cellular and molecular mechanisms underlying tolerance to, and dependence upon, a wide spectrum of psychotropic drugs of abuse. The common neuroanatomical pathways involved, and the adaptive processes that occur at the receptor level, are discussed, together with how such features relate to the clinical problem. This is the third in the "Neurosciences Perspectives" and in common with the aims of the series provides up-to-date reviews of its topical subject from the biochemical and pharmacological points of view, with the historical perspective and prospects for clinical application.