This book offers you more of what you need, less of what you don't! It is written by leading personalities in the field. Focusing on the structure and function of the cell, this radically new approach to cell biology offers a comprehensive, full-colour look at the subject and the latest developments in the field. It emphasises specific macromolecular interactions and their relation to cellular structure and function, and covers such areas as chemical building blocks, assembly, major organelles and components of the cell, cell cycle, cellular regulation, gene expression, viruses, energy interconversions, and more. It is now available as a revised reprint.
Auflage
Sprache
Verlagsort
Verlagsgruppe
Elsevier - Health Sciences Division
Zielgruppe
Für höhere Schule und Studium
Medical students
Editions-Typ
Illustrationen
Maße
Höhe: 276 mm
Breite: 216 mm
Gewicht
ISBN-13
978-1-4160-2388-3 (9781416023883)
Copyright in bibliographic data is held by Nielsen Book Services Limited or its licensors: all rights reserved.
Schweitzer Klassifikation
Thomas D. Pollard
MD, Professor, Department of Molecular, Cellular, and Developmental Biology, Yale University, New Haven, CT
William C. Earnshaw
PhD, FRSE, Professor and Wellcome Principal Fellow, Institute of Cell and Molecular Biology, University of Edinburgh, Edinburgh, UK
1. General Principles of Cellular Organization BASIC CHEMICAL AND PHYSICAL CONCEPTS 2. Basic Biophysical Concepts 3. Molecular Structures 4. Macromolecular Assembly 5. Research Strategies MEMBRANE STRUCTURE AND FUNCTION 6. Membrane Structure and Dynamics 7. Membrane Pumps 8. Membrane Carriers 9. Membrane Channels 10. Membrane Physiology STORAGE AND EXPRESSION OF GENETIC INFORMATION 11. Introduction to Nuclear Structure and Function 12. Chromosome Organization 13. Packaging the DNA into Chromosomes 14. Gene Expression 15. RNA Processing 16. Information Flow Between Nucleus and Cytoplasm BIOGENESIS, TRAFFIC AND FUNCTIONS OF CELLULAR MEMBRANE SYSTEMS 17. Introduction to Membrane Compartments 18. Protein Synthesis and Folding in the Cytoplasm 19. Post-Translational Targeting of Proteins to Organelles 20. Co-Translational Import into the Endoplasmic Reticulum 21. Endoplasmic Reticulum to Golgi 22. Trans-Golgi Network and Beyond 23. Endocytosis 24. Degradation of Cellular Components RECEPTION AND TRANSDUCTION OF ENVIRONMENTAL INFORMATION 25. Signaling Overview 26. Plasma Membrane Receptors 27. Protein Hardware for Signaling 28. Second Messengers 29. Integration of Signals CELLULAR INTERACTIONS WITH NEIGHBORS AND THEIR ENVIRONMENT 30. Introduction to Cellular Adhesion and the Extracellular Matrix 31. Extracellular Matrix Molecules 32. Cellular Adhesion 33. Intercellular Junctions 34. Connective Tissues CYTOSKELETON AND CELLULAR MOTILITY 35. Overview of the Cytoskeleton and Cellular Motility 36. Actin and Actin-Binding Proteins 37. Microtubules and Microtubule-Associated Proteins 38. Intermediate Filaments 39. Motor Proteins 40. Intracellular Motility 41. Cellular Motility 42. Muscles CELL CYCLE 43. Introduction to the Cell Cycle 44. The GI Phase and Cell Cycle Regulation 45. S and DNA Replication 46. The G2 Phase 47. Mitosis and Cytokinesis 48. Meiosis 49. Programmed Cell Death
