Part One: Introduction Introduction to Vibrational Spectroscopy
Peter R. Griffiths
Part Two: Drug Discovery
Sampling Techniques and Fiber-Optic Probes
John M. Chalmers and Peter R. Griffiths
Vibrational Spectroscopy in the Discovery Phase Component of Pharmaceutical Research
Don E. Pivonka
Applications of Vibrational Spectroscopy to Combinatorial Chemistry
Don E. Pivonka
Vibrational Spectroscopic Analysis for the Determination of Structure-Activity Relationships (SARs) in Molecular Binding
Don E. Pivonka and Isao Noda
Applications of Vibrational Optical Activity in the Pharmaceutical Industry
Laurence A. Nafie and Rina K. Dukor
Characterization and Optimization of Chemical Synthesis Using Real-Time Vibrational Spectroscopy
Fadi Homsi, Paul Barrett, Jian Wang and Roel Ferwerda
Part Three: Drug Development
Infrared and Raman Spectroscopy for Process Development
George Zhou, Robert Guenard and Zhihong Ge
The Analysis of Pharmaceutical Substances and Formulated Products by Vibrational Spectroscopy
Don Clark and Alexander Pysik
Raman Analysis of Pharmaceuticals
David E. Bugay, Jan-Olav Henck, Michael L. Longmire and Fiona C. Thorley
Vibrational Spectroscopy of Solid-State Forms - Introduction, Principles and Overview
Terry L. Threlfall and John M. Chalmers
Vibrational Spectroscopy of Solid-State Forms - Applications and Examples
David H. Igo and Pingyun Chen
Pharmaceutical Applications of Chemical Mapping and Imaging
Don Clark, Mark Henson, Fred LaPlant, Slobodan Sasic and Lin Zhang
Terahertz Spectroscopy for Pharmaceutical Applications
Mike Claybourn, Husheng Yang, Lubomir Gradinarsky, Jonas Johansson and Staffan Folestad
Part Four: Conclusions
History, Trends and Prognostications
Peter R. Griffiths, John M. Chalmers and Don E. Pivonka
