Part 1 Structure and function of the large intestine: embryology and developmental abnormalities of the large intestine, R.A. Cobb and R.C.N. Williamson; gross and microscopic anatomy of the large intestine, J. Christensen; structure-function relationships - lessons from other species, Michael I. McBurney and Peter J. Van Soest; the colonic flora, fermentation, and large bowel digestive function, G.T. McFarlane and J.H. Cummings; motor functions of the colon, Jan D. Huizinga and Edwin E. Daniel; functions of the anorectum - defecation and continence, Ghislain Devroede; colonic fluid and electrolyte transport in health and disease, Henry J. Binder, et al; regulation of colonic transport by the autonomic nervous system, Helen J. Cooke; response of the colon to injury - inflammation, immunity, and mucus, Steven R. Martin and W. Allan Walker. Part 2 General clinical features of colo-rectal disease: limitations of epidemiologic methods in the study of colonic disorders, Albert I. Mendeloff; diet, fibre and colorectal disease - critical appraisal, Martin Eastwood; radiology of the large intestine, Claire E. Bender; endoscopy of the colon, Jonathan E. Clain; clinical application of diagnostic tests in selected colonic disorders, J.B. Kirsner and M.O. Blackstone; value of colorectal biopsies - a critical appraisal, Teri A. Longacre and Cecilia M. Fenoglio-Preiser; screening for colorectal disease; Douglas B. McGill and David A. Ahlquist. Part 3 Specific diseases of the large intestine: novel aspects of the pathophysiology of parasitic infections of the colon, Stephen M. Collins; parasitic infections of the large intestine, Henry Zaiman and Roy G. Shorter; bacterial infections - pathophysiology, clinical features and treatment, Mitchell B. Cohen, et al; infections of the large intestine in the immunocompromised host, Phillip D. Smith, et al; etiology of chronic ulcerative colitis and Crohn's Disease, V.S. Chadwick; challenges in inflammatory bowel diseases, Gary Gitnick; critical evaluation of the medical therapy of inflammatory bowel disease, Henry D. Janowitz and Jeffrey J. Bilotta; etiology of large bowel cancer, Dennis J. Ahnen; neoplasia of the colorectum - natural history and prognosis of colorectal cancer, Richard E. Wilson and John H. Donohue; diverticular disease of the colon, Adam N. Smith; megacolon, Sidney F. Phillips; irritable bowel syndrome, W. Grant Thompson; bleeding from the colon, Paul C. Shellito and Leslie W. Ottinger. (Part contents).
