Contents
Preface, ix
Contributors, xi
Part I Function and Structural Neurophotonic Imaging
Chapter 1 ? Miniaturized Optical Neuroimaging Systems 3
Hang Yu, Janaka Senarathna, Betty M. Tyler, Nitis h V. Thakor, and Arvi nd P. Pathak
Chapter 2 ? Functional Imaging with Light-Sheet Microscopy 21
Raghav K. Chhetri and Philipp J. Keller
Chapter 3 ? Two-Photon Microscopy in the Mammalian Brain 55
Hod Dana and Shy Shoham
Chapter 4 ? Light Field Microscopy for In Vivo Ca2+ Imaging 81
Tobi as Noebauer and Alip asha Vaziri
Chapter 5 ? Genetically Encoded Activity Indicators 113
Chenchen Song and Thomas Knoepfel
Chapter 6 ? Functional Optoacoustic Imaging 129
Daniel Razansky
Chapter 7 ? Imaging Deep in the Brain with Wavefront Engineering 147
Roarke Horstmeyer, Maximi llian Hoffmann, Haowen Ruan, Benjami n Judkewitz,
and Changhuei Yang
Chapter 8 ? Nanoscopic Imaging to Understand Synaptic Function 173
Daniel Choquet and Anne-Sophie Hafner
Chapter 9 ? Chemical Clearing of Brains 191
Klaus Becker, Chris tian Hahn, Nina Jaehrling, Marko Pende,
Inna Sabdyusheva-Litsc hauer, Saiedeh Saghafi, Martina Wanis , and Hans-Ulric h Dodt
Chapter 10 ? Advanced Light-Sheet Microscopy to Explore Brain
Structure on an Organ-Wide Scale 221
Ludovic o Silvestri and Francesc o S. Pavone
Part II Neurophotonic Control and Perturbation
Chapter 11 ? Optogenetic Modulation of Neural Circuits 235
Mathias Mahn, Oded Klavi r, and Ofer Yizhar
Chapter 12 ? Molecular Photoswitches for Synthetic Optogenetics 271
Shai Berlin and Ehud Y. Isacoff
Chapter 13 ? Applications of Nanoparticles for Optical Modulation of
Neuronal Behavior 293
Chiara Pavi olo, Shaun Gietman, Daniela Duc, Sim on E. Moulton, and
Paul R. Stoddart
Chapter 14 ? Optical Stimulation of Neural Circuits in Freely Moving
Animals 317
Leore R. Heim and Eran Stark
Chapter 15 ? Holographic Optical Neural Interfaces (HONIs) 333
Shani Rosen, Shir Paluch, and Shy Shoham
Chapter 16 ? Multi-Photon Nanosurgery 353
Anna Letizia Allegra Masc aro and Francesc o Saverio Pavone
Part III Clinical and Human Neurophotonics
Chapter 17 ? High Resolution Diffuse Optical Tomography of the
Human Brain 369
Muriah D. Wheelock and Adam T. Eggebrecht
Chapter 18 ? Human Brain Imaging by Optical Coherence Tomography 399
Caroline Magnain, Jean C. Augustinack, Davi d Boas, Bruce Fisc hl, Taner Akkin,
Ender Konukoglu, and Hui Wang
Chapter 19 ? Acousto-Optic Cerebral Monitoring 439
Mic hal Balberg and Revi tal Pery-Shechter
Chapter 20 ? Neurophotonic Vision Restoration 459
Adi Schejter Bar-Noam and Shy Shoham
Chapter 21 ? Optical Cochlear Implants 473
C.-P. Ric hter, Y. Xu, X. Tan, N. Xia, and N. Suematsu
Chapter 22 ? Label-Free Fluorescence Interrogation of Brain Tumors 503
Brad A. Hartl, Shami ra Sridharan, and Laura Marcu
Chapter 23 ? Higher Harmonic Generation Imaging for Neuropathology 527
Nikolay Kuzmi n, Sander Idema, Eleonora Aronic a, Philip C. de Witt Hamer,
Pieter Wess eling, and Marie Louis e Groot
INDEX, 545