Current Aspects of the Neurosciences: v. 4

The articles in this volume have a bias towards neuropharmacology. The role of gangliosides in the central nervous system is critically discussed in two chapters, one article concentrating more on their involvement in neuroplasticity and pathology and the other on their interactions with cellular calcium. Chapters four to eight deal with an animal model involving the use of pilocarpine in the inducement of seizures and its relevance to epilepsy, the way neuroleptics induce movement disorders, the way anti-depressants are thought to work and the way in which the neuroendocrine system is involved in dementia. Two techniques described, "in situ" hybridization and the use of oocytes for characterizing receptor-mediated mechanisms, have yielded a wealth of information. It is appropriate, therefore, that both of these procedures are examined in this book.