Acknowledgments xi
1 Investigating Practice: The Cognitive-Cultural Systems of the Research Lab 1
2 Building Hybrid Simulation Devices: Distributed Model-Based Reasoning 47
3 Engineering Concepts: Conceptual Innovation in a Neuroengineering Lab 105
4 Interlude: Building "the Lab" 145
5 Managing Complexity: Modeling Biological Systems Computationally 173
6 The Bimodal Model-Building Strategy 233
7 Interdisciplinarities in Action 281
Notes 319
References 335
Index 355
