This is a comprehensive reference that includes the basic science, clinical features, imaging, pathology and treatment of specific viral entities affecting the central nervous system (CNS). It will assist professionals in their attempt to identify, examine and manage viral CNS infections and unravel the therapeutic and diagnostic challenges associated with viral CNS disorders.
Key Features
Features MRI scans, histopathology and lined diagrams showing pathophysiology
Much has happened in our understanding of CNS infections in recent years and a comprehensive book that covers the entire subject is much needed.
There is ongoing interest in infectious disease. The increasing globalization of medicine is putting demands on many more people to become familiar with issues from around that world that they did not see in training.
Rezensionen / Stimmen
This second edition is a wonderful comprehensive reference for practicing neurologists and infectious disease specialists when faced with patients afflicted with viral-mediated neurological syndromes. A significant upgrade from the first edition, this edition includes newer topics, including West Nile, Ebola, Zika, enterovirus D68, and SARS-CoV-2 viruses, as well as significant advances in methodologies of detection and treatment. Drs. Nath and Berger have provided a very broad coverage to this topic, reflecting their clinical and scientific background, keeping both the clinical and scientific practitioners in mind. This text holds its own as a solidly comprehensive reference text for clinicians, including neurologists and infectious disease specialists, as well as for the immunologist and clinical scientist involved in the pathophysiology of virally mediated neurological illnesses. The editors are well-renowned neuroinfectious specialists in theirnfield who have sought experts from around the world to help contribute chapters to this text. There is a lack of textbooks in this area, and having an authoritative work helps the field progress further, especially with the advances made since the last edition was published in 2003.
Ali A Saherwala, MD(Thomas Jefferson University)
Auflage
Sprache
Verlagsort
Verlagsgruppe
Zielgruppe
Für höhere Schule und Studium
Für Beruf und Forschung
Professional Reference
Illustrationen
2 farbige Tabellen, 54 s/w Tabellen, 31 farbige Abbildungen, 63 s/w Abbildungen
2 Tables, color; 54 Tables, black and white; 31 Illustrations, color; 63 Illustrations, black and white
Maße
Höhe: 280 mm
Breite: 210 mm
Gewicht
ISBN-13
978-1-4987-3316-8 (9781498733168)
Copyright in bibliographic data and cover images is held by Nielsen Book Services Limited or by the publishers or by their respective licensors: all rights reserved.
Schweitzer Klassifikation
Avindra Nath
Dr. Nath is the Chief of the Section of Infections of the Nervous System at the National Institute of Neurological Disorders and Stroke. He was previously Professor in the Department of Neurology and Director of the Division of Neuroimmunology and Neurological Infections at Johns Hopkins University. His career has been dedicated to studying the clinical manifestations, pathophysiology and developing treatment for brain infections since the beginning of the AIDS pandemic. He has traveled to several countries to study these infections including Liberia during the Ebola epidemic. He teaches medical students, residents and clinical fellows on CNS infections for which he has received several teaching awards. He frequently talks at grand rounds, seminars and conferences around the world on viral infections of the brain and has been teaching courses on viral encephalitis at the American Academy of Neurology for over 20 years. His laboratory research is focused mainly on retroviral infections particularly HIV infection. More recently, his laboratory is studying the pathophysiology of Ebola and Zika viruses. He is the past President of the International Society of Neurovirology (ISNV) and an elected member of the Association of American Physicians. He is the recipient of the Pioneer award from the ISNV and the Wybran award from the Society of Neuroimmune Pharmacology.
Joseph R. Berger
Dr. Berger, M.D., is Professor of Neurology and Associate Chief of the Multiple Sclerosis Division of the Department of Neurology at the Perelman School of Medicine at the University of Pennsylvania in Philadelphia. His career has been dedicated to the diagnosis, treatment and investigation of neuroinfectious and neuroinflammatory disorders. His foray into neuroinfectious diseases started with the investigation of the neurological complications of HIV/AIDS while at the University of Miami at the inception of the AIDS pandemic and an endowment there established the Whigham-Berger Endowed Chair, the first endowed chair for the study of the neurological complications of HIV/AIDS. Dr. Berger continued his research in HIV and PML while at the University of Kentucky where he was Chairman of the Department of Neurology from 1995 to 2013. With Dr. Robert Levy, he co-founded and co-chaired the international Neuroscience of HIV conference. He is a fellow of the American College of Physicians, American Academy of Neurology and the American Neurological Association. Among his many awards are the Pioneer Award from the International Society of Neurovirology and the Distinguished Teaching Award from the American Neurological Association.
Herausgeber*in
Nat. Inst. of Health, USA
University of Pennsylvania, Philadelphia, USA
INTRODUCTION: EPIDEMIOLOGY, SOCIOECONOMIC IMPACT, AND CHALLENGES AHEAD. Introduction to virus structure, classification, replication, and hosts. Neuropathogenesis of viral infections. An approach to pathogen discovery for viral infections of the nervous system. Neuropathology of CNS viral infections and the role of brain biopsy in the diagnosis. DNA VIRUSES. Herpes simplex viruses. Varicella zoster virus infection. Epstein-Barr virus and the nervous system. Cytomegalovirus. Progressive multifocal leukoencephalopathy. Adenovirus. RETROVIRUSES. HIV neurological complications. Human T lymphotropic virus type 1 (HTLV-1). RNA VIRUSES. Rabies and other lyssaviruses. Neurological manifestations of West Nile virus. Chikungunya virus and Japanese encephalitis virus. Arthropod-borne virus encephalitis. Enteroviruses. Measles and its neurological complications. Rubella. Influenza neurologic complications. Nipah encephalitis, a fatal encephalitis with bats as reservoir. MISCELLANEOUS. Von Economo's encephalitis. Neurological events following immunizations. Central nervous system viral infections complicating immunosuppression. Post-viral syndromes. Viral neuro-oncogenesis: Polyomaviruses and brain tumors. Autoimmune disorders that can be mistaken for viral illness. Antiviral therapeutics for viral infections of the central nervous system. Neurological manifestations of coronavirus infections
