Chemistry and Biochemistry of Flavoenzymes summarizes the present knowledge of the chemical and physical properties of free flavin, modified flavins occurring in nature, and deazaflavin. This information forms the fundamental basis for understanding the catalytic properties of flavoenzymes. Flavoproteins involved in transport, electron transfer, oxidation, dehydrogenation and hydroxylation reactions are discussed with respect to their biochemical and biophysical properties. The book presents the catalytic mechanisms of the flavoproteins in detail and, where available, three-dimensional structures and molecular biology data are included. The medical aspects of free and protein-bound flavin are also briefly discussed. Chemistry and Biochemistry of Flavoenzymes is an essential reference source for chemists, biochemists, toxicologists, biologists, pharmacologists, and researchers in the pharmaceutical industry.
Sprache
Verlagsort
Verlagsgruppe
Zielgruppe
Für höhere Schule und Studium
Für Beruf und Forschung
Illustrationen
11 s/w Photographien bzw. Rasterbilder, 102 s/w Tabellen
11 figs., 102 tabs.
Maße
Höhe: 254 mm
Breite: 178 mm
Gewicht
ISBN-13
978-0-8493-4393-3 (9780849343933)
Schweitzer Klassifikation
VOLUME I: Free Flavins: Syntheses, Chemical and Physical Properties. Structure, Synthesis, and Physical Properties of Covalently-Bound Flavins and 6- and 8-Hydroxyflavins. Roseoflavin, Nekoflavin, and Schizoflavin. Syntheses and Properties of 5-Deazaflavins. The Photochemistry of Flavins. Flavin Metabolites. Medical Aspects of Vitamin B2. Biosynthesis of Flavins. Methods Used to Reversibly Resolve Flavoproteins into the Constituents Apoflavoproteins and Prosthetic Group. Flavoproteins in Medicine. Riboflavin-Binding Proteins. The Lumazine/Riboflavin Synthase Complex of Bacillus Subtilis. DNA Photolyase and the Role of Flavin in DNA Repair. Cellobiose Oxidoreductase. Riboflavin Kinase and FAD Synthetase. Mammalian Methylenetetrahydrofolate Reductase. 5,10-Methylenetetrahydrofolate Reductases: Iron-Sulfur-Zinc Flavoproteins of Two Acetogenic Clostridia. Redox Properties of Flavins and Flavoproteins.