Introduction (Peter Muir).
Chapter 1: Morphology and function of the cruciate ligaments (Hilde de Rooster, Henri Van Bree).
Chapter 2: Biomechanics of the cruciate ligaments (Susannah J. Sample, Ray Vanderby Jr, Peter Muir).
Chapter 3: Cruciate ligament remodeling and repair (Connie S. Chamberlain, Ray Vanderby Jr.).
Chapter 4: Meniscal structure and function (Antonio Pozzi, James L. Cook).
Chapter 5: Biomechanics of the normal and cranial cruciate-deficient stifle (Antonio Pozzi, Stanley E. Kim).
Section II: Etiopathogenesis of Cruciate Ligament Rupture.
Introduction (Peter Muir).
Chapter 6: Histology of cranial cruciate ligament rupture (Kei Hayashi, Peter Muir).
Chapter 7: Genetics of cranial cruciate ligament rupture (Vicki Wilke).
Chapter 8: Cruciate ligament matrix metabolism and development of laxity (Eithne Comerford).
Chapter 9: Stifle morphology (Eithne Comerford).
Chapter 10: Role of nitric oxide production and matrix protease activity in cruciate ligament degeneration (David E. Spreng).
Chapter 11: Role of antibodies to collagen type I and II (Hilde De Rooster, Tanya de Bruin, Eric Cox).
Chapter 12: Synovitis or stifle instability, which comes first? (Jason A. Bleedorn, Peter Muir).
Chapter 13: Role of synovial immune responses in stifle synovitis (Peter Muir)
Section III: Clinical Features
Introduction (Peter Muir).
Chapter 14: Epidemiology of cranial cruciate ligament rupture (James L. Cook).
Chapter 15: History and clinical signs of cruciate ligament rupture (Peter Muir).
Chapter 16: Partial versus complete rupture of the cranial cruciate ligament (Peter Muir).
Chapter 17: Caudal cruciate ligament rupture (Peter Muir).
Chapter 18: Stress radiography of the stifle (Ingrid Gielen, Jimmy Saunders, B. Van Ryssen, Henri van Bree).
Chapter 19: Stifle ultrasonography (Cristi R. Cook).
Chapter 20: Computed tomography (CT) of the stifle (Ingrid Gielen, Jimmy Saunders, Bernadette van Ryssen, Henri van Bree).
Chapter 21: Magnetic resonance imaging of the stifle (Peter V. Scrivani).
Section IV: Surgical Treatment
Introduction (Peter Muir).
Chapter 22: Arthroscopy versus arthrotomy for surgical treatment (Brian S. Beale, Don A. Hulse).
Chapter 23: Joint Lavage (Peter Muir).
Chapter 24: Extracapsular stabilization (James L. Cook).
Chapter 25: Tibial plateau leveling osteotomy (Milan Milovancev, Susan L. Schaefer).
Chapter 26: Tibial tuberosity advancement (Randy J. Boudrieau).
Chapter 27: Intra-articular stabilization (Paul A. Manley).
Chapter 28: Biomechanics of the cranial cruciate ligament deficient stifle treated by tibial osteotomies (Antonio Pozzi, Stanley E. Kim).
Chapter 29: Arthroscopic follow-up after surgical stabilization of the stifle (Brian S. Beale, Don A. Hulse).
Chapter 30: Cranial cruciate ligament debridement (David E. Spreng).
Chapter 31: Surgical treatment of concurrent meniscal injury (James L. Cook, Antonio Pozzi).
Chapter 32: Meniscal Release (Antonio Pozzi, James L. Cook).
Chapter 33: Progression of arthritis after stifle stabilization surgery (John F. Innes).
Chapter 34: Residual lameness after stifle stabilization surgery (Michael G. Conzemius, Richard B. Evans).
Section V: Medical Management of Cruciate Rupture
Introduction (Peter Muir).
Chapter 35: Medical therapy for stifle arthritis (Gail H. Jaeger, Steven C. Budsberg).
Chapter 36: Rehabilitation for dogs with cranial cruciate ligament rupture (Courtney J. Arnoldy).
Section VI: Future Directions
Introduction (Peter Muir).
Chapter 37: Client-specific outcome measures (John F. Innes).
Chapter 38: Total knee replacement in the dog (Matthew J. Allen, Katy L. Townsend, William D. Liska).
Chapter 39: Regenerative medicine and cranial cruciate ligament repair (Martha M. Murray).
Chapter 40: Disease-modifying medical therapy (Sara Colopy).
