Editorial: Schmid, M.; Preface: Muenke, M.; Kress, W.; Collmann, H.; Solomon, B.D.; Foreword: Cohen Jr., M.M.; Craniosynostosis: A Historical Overview: Solomon, B.D.; Collmann, H.; Kress, W.; Muenke, M.; Discovery of MSX2 Mutation in Craniosynostosis: A Retrospective View: Muller, U.; Regulation of Calvarial Bone Growth by Molecules Involved in the Craniosynostoses: Benson, M.D.; Opperman, L.A.; Signal Transduction Pathways and Their Impairment in Syndromic Craniosynostosis: Connerney, J.J.; Spicer, D.B.; The Molecular Bases for FGF Receptor Activation in Craniosynostosis and Dwarfism Syndromes: Beenken, A.; Mohammadi, M.; Recurrent Germline Mutations in the FGFR2/3 Genes, High Mutation Frequency, Paternal Skewing and Age-Dependence: Arnheim, N.; Calabrese, P.; Apert, Crouzon, and Pfeiffer Syndromes: Cohen Jr., M.M.; Muenke Syndrome: Solomon, B.D.; Muenke, M.; Saethre-Chotzen Syndrome: Clinical and Molecular Genetic Aspects: Kress, W.; Collmann, H.; Craniofrontonasal Syndrome: Molecular Genetics, EFNB1 Mutations and the Concept of Cellular Interference: Wieland, I.; Uncommon Craniosynostosis Syndromes: A Review of Thirteen Conditions: Raam, M.S.; Muenke, M.; Metopic Craniosynostosis Syndrome Due to Mutations in GLI3: McDonald-McGinn, D.M.; Feret, H.; Nah, H.-D.; Zackai, E.H.; Craniosynostosis and Chromosomal Alterations: Passos-Bueno, M.R.; Fanganiello, R.D.; Jehee, F.S.; Nonsyndromic Craniosynostoses: Collmann, H.; Solomon, B.D.; Schweitzer, T.; Kress, W.; Muenke, M.; Molecular Genetic Testing of Patients with Craniosynostosis: Hehr, U.; Prenatal Sonographic Diagnosis of Craniosynostosis: Schramm, T.; Clinical Approach to Craniosynostosis: Gripp, K.W.; Imaging Studies and Neurosurgical Treatment: Collmann, H.; Schweitzer, T.; Bohm, H.; Maxillofacial Examination and Treatment: Bohm, H.; Schweitzer, T.; Kubler, A.; Author and Subject Index.