Part 1 Concept of schizophrenia: the concept of schizophrenia and the development of DSM-IV, N.C. Andreasen and M.A. Flaum. Part 2 Brain imaging and morphology: developments in neuroanatomical schizophrenic research - a brief review, B. Bogets; exploratory data analysis to identify subtypes of pathophysiology in schizophrenic - support for the coexisting three-syndrome concept, R. Toyoshima et al; metabolic imaging in positron emission tomography in schizophrenia, M.S. Buchsbaum et al; positron emission tomographic studies on cortical control of saccade in schizophrenia, Y. Nakashima et al; simple reaction time and regional cerebral blood flow in patients with schizophrenia, M. Kurachi et al. Part 3 Pathophysiology: the place of psychology in biological studies of schizophrenia, P.S. Holzman; smooth pursuit eye movements and control of express saccades in schizophrenic patients, Y. Matsue; psychophysiological classifications and syndromes in schizophrenia, J.H. Gruzelier; dynamic event-related potential topography in schizophrenia - special reference to P300, C. Ogura and H. Ohta; reproduction of psychophysiological signs in animals - implication for a noradrenaline hypothesis of schizophrenia, K. Yamamoto et al. Part 4 Neurochemistry and psychopharmacology: chronic methamphetamine intoxication in monkeys as an animal model of schizophrenia, Y. Machiyama; neurotransmitter dysfunctions in schizophrenia, A. Carlsson; schizophrenic psychosis - speculative new evidence to support the glutamatergic hypothesis of pathophysiology, C.A. Tamminga et al; disturbed neurotransmission via N-methyl-D-aspartate receptor and schizophrenia, T. Nishikawa et al; experimental studies of methamphetamine-induced behavioural sensitization as a model of vulnerability to relapse of schizophrenia, K. Akiyama et al; a clinical and biochemical model of relapse prediction in schizophrenia - a role for CSF interneukin 2?, D.P. van Kammen et al; effects of typical/atypical neuroleptics on the functioning of central dopamine systems - possible relevance of clinical effects, B.S. Bunney; preferential dopaminergic activation by clozapine in the medial prefrontal cortex - an in vivo microdialysis study, T. Koyama et al; occurrence of neuropeptides and growth factors in relation to mesencephalic dopamine neurons, T. Hukfelt et al; cholecystokinin and met-enkephalin in schizophrenic postmortem brains, H. Shibuya and M. Toru; possible involvement of mesocortical dopaminergic system in methamphetamine-induced behavioural sensitization - with special reference to the functional relationship of mesocortical dopaminergic system and CCK neurons in the forebrain, T. Moroji et al.
