With cutting-edge contributions from internationally recognized experts and field pioneers, Amyotrophic Lateral Sclerosis is the definitive guide to the subject. Formatted in an easily accessible manner, with summaries of key points at the end of each chapter, this guide covers all the essential information clinicians require for daily practice, as well as providing a reader-friendly approach to every aspect of ALS with detailed sections on the clinical features of disease, translational research, patient care and management, and emerging therapies.
Sprache
Verlagsort
Verlagsgruppe
Zielgruppe
Für Beruf und Forschung
Professional Practice & Development
Maße
Höhe: 254 mm
Breite: 178 mm
Dicke: 46 mm
Gewicht
ISBN-13
978-0-367-39184-3 (9780367391843)
Copyright in bibliographic data and cover images is held by Nielsen Book Services Limited or by the publishers or by their respective licensors: all rights reserved.
Schweitzer Klassifikation
Hiroshi Mitsumoto, Serge Przedborski, Paul H. Gordon
Overview of Clinical ALS. History. Epidemiology. Pathology. Clinical Features: Motor System. Clinical Features: Dementia and Cognitive Deficits. Familial ALS and Genetic Approaches to ALS. Electrophysiology and Other Objective Markers. Classification, Diagnosis and Presentation of Diagnosis of ALS. Natural History. Translational Research in ALS: Mechanisms behind therapy. Motor Neuron: The origin, definition and function. Neurodegeneration. Excitotoxicity. Oxidative Stress. Neuroinflammation.
Apoptosis. Cytoskeleton. Mitochondria. Environmental Neurotoxicity. Genetic Causes and Predisposition. Protein Aggregate Disease. Proteiomic and Metabolomic Approach.
Infections and Autoimmunity. Gene Transfer Technology. High Through-put Technology. Animal Models. Restoration-Practical Approach. Clinical Trial Methodology. ALS Therapy: Care and Management. Multidisciplinary Approach: Ideal Care Centers and World Perspective. Impact of National ALS Care Database and Practice Parameters. Symptomatic Pharmacotherapy: Bulbar and Constitutional Symptoms. Pharmacotherapy: In clinical trials. Physical Rehabilitation. Speech Therapy and Augmentative Communication/Assistive Technology. Nutritional treatment: Theoretical and Practical issues. Respiratory care: Basic and Practical. Psychosocial care: Patient and Caregiver Support. Palliative Care. Palliative Care: Family Perspective. Decision Making for End of Life. National ALS Study Group: Future of ALS Clinical Research
