Targeting Intercellular Communication with Nanomedicine and Advanced Therapeutics

Targeting Intercellular Communication with Nanomedicine and Advanced Therapeutics delves into the complex world of intercellular communication biology and its implications on therapeutics. Despite significant progress in this field, there has been a lack of comprehensive understanding of the connections between different forms of communication and their role in diseases such as cancer, neurological disorders, metabolic diseases, and inflammatory/immune diseases. This book bridges this gap by providing equal insight into all areas of intercellular communication and the therapeutics in development aimed at these different forms of communication. The book is organized into fourteen chapters, covering a wide range of topics, including an introduction to the field, biological targets, challenges and approaches to overcoming biological barriers, and the significance of contact points and mechanisms of internalization. It delves into the specifics of tunneling nanotubes, extracellular vesicles, and the immune and non-immune interface in various diseases. Furthermore, it explores the crosstalk of different forms of intercellular communication and the implications of mitochondrial exchange in each of the four primary pathological areas. Targeting Intercellular Communication with Nanomedicine and Advanced Therapeutics is an essential resource for researchers, students, and professionals in the field of drug development and delivery. By connecting the dots between extracellular vesicles, tunneling nanotubes, and cell-cell junctions, this book serves as a foundation for further advancements in the science of intercellular communication and it's applications to new drug discovery and delivery. Biologists will also benefit from the way this book connects intercellular communication processes with therapeutic pathways.