This book presents a unique introduction into the field of bioinorganic chemistry through practical laboratory experiments. Topics include many aspects of modern bioinorganic chemistry such as model systems for metalloenzymes, biosensors, metal bioconjugates and metal-based drugs. Each chapter contains a brief introduction, followed by detailed experimental procedures, completed with all necessary background information for the student as well as their instructors. A valuable supplement to standard textbooks of inorganic and bioinorganic chemistry Essential for all instructors teaching laboratory courses in general and inorganic chemistry
Rezensionen / Stimmen
"This delightful book breaks new ground as it is the first lab manual devoted entirely to experiments in bioinorganic chemistry."Richard S. Herrick in: Journal of Chemical Education 2010 "Ein sehr gutes Buch."Siegfried Schindler in: Nachrichten aus der Chemie 5/2010 "Insgesamt ist das Buch sehr empfehlenswert für Lehrende und Lernende der bioanorganischen Chemie, wenn man das Thema nicht nur in einer Vorlesung oder einem Seminar erschöpfen will, sondern auch praktisch lehren und lernen möchte."Axel Klein in: Angewandte Chemie 122/2010
Sprache
Verlagsort
Zielgruppe
Für höhere Schule und Studium
US School Grade: From College Freshman to College Senior
Illustrationen
5
46 s/w Abbildungen, 5 s/w Tabellen
46 b/w ill., 5 b/w tbl.
Maße
Höhe: 246 mm
Breite: 175 mm
Dicke: 14 mm
Gewicht
ISBN-13
978-3-11-020954-9 (9783110209549)
Schweitzer Klassifikation
Nils Metzler-Nolte, Ruhr University, Bochum, Germany; Ulrich Schatzschneider, Ruhr University, Bochum, Germany
Frontmatter
Table of Contents
1. Introduction
2. Small molecule activation and inactivation by metalloenzymes and their model compounds
3. Carbon monoxide and nitric oxide as small molecule messengers
4. Metallointercalators as DNA probes
5. DNA manipulation with metal complexes
6. Synthesis of metal-peptide bioconjugates
7. Preparation of metal-protein bioconjugates
8. Electrochemical investigation of metal complexes
9. Metal complexes with anti-proliferative activity
Backmatte