Pathophysiology

PART ONE: CENTRAL CONCEPTS OF PATHOPHYSIOLOGY: CELLS AND TISSUES * THE CELL * Cellular Biology * Altered Cellular and Tissue Biology * The Cellular Environment: Fluids and Electrolytes, Acids and Bases * GENES AND GENE-ENVIRONMENT INTERACTION * Genes and Genetic Diseases * Genes, Environment, and Common Diseases * MECHANISMS OF SELF-DEFENSE * Immunity * Inflammation * Infection and Alterations in Immunity and Inflammation * Stress and Disease * CELLULAR PROLIFERATION: CANCER * Tumor Biology * Tumor Invasion and Metastasis * Cancer in Children * PART TWO: PATHOPHYSIOLOGIC ALTERATIONS: ORGANS AND SYSTEMS * THE NEUROLOGIC SYSTEM * Structure and Function of the Neurologic System * Pain, Temperature Regulation, Sleep, and Sensory Function * Concepts of Neurologic Dysfunction * Alterations of Neurologic Function * Neurobiology of Schizophrenia, Mood Disorders, and Anxiety Disorders * Alterations of Neurologic Function in Children * THE ENDOCRINE SYSTEM * Mechanisms of Hormonal Regulation * Alterations of Hormonal Regulation * THE REPRODUCTIVE SYSTEMS * Structure and Function of the Reproductive Systems * Alterations of the Reproductive Systems * Sexually Transmitted Infections * THE HEMATOLOGIC SYSTEM * Structure and Function of the Hematologic System * Alterations of Erythrocyte Function * Alterations of Leukocyte, Lymphoid, and Hemostatic Function * Alterations of Hematologic Function in Children * THE CARDIOVASCULAR AND LYMPHATIC SYSTEMS * Structure and Function of the Cardiovascular and Lymphatic Systems * Alterations of Cardiovascular Function * Alterations of Cardiovascular Function in Children * THE PULMONARY SYSTEM * Structure and Function of the Pulmonary System * Alterations of Pulmonary System * Alterations of Pulmonary System in Children * THE RENAL AND UROLOGIC SYSTEM * Structure and Function of the Renal and Urologic Systems * Alterations of Renal and Urinary Tract Function * Alterations of Renal and Urinary Tract Function in Children * THE DIGESTIVE SYSTEM * Structure and Function of the Digestive System * Alterations of Digestive Function * Alterations of Digestive Function in Children * THE MUSCULOSKELETAL SYSTEM * Structure and Function of the Musculoskeletal System * Alterations of Musculoskeletal Function * Alterations of Musculoskeletal Function in Children * THE INTEGUMENTARY SYSTEM * Structure, Function, and Disorders of the Integument * Alterations of Integument in Children * MULTIPLE INTERACTING SYSTEMS * Shock, Multiple Organ Dysfunction Syndrome, and Burns in Adults * Shock, Multiple Organ Dysfunction Syndrome, and Burns in Children