The role of cytokines in inflammatory glomerular injury, F.G. Lakkis and S.N. Coelho; role of leukotrienes and lipoxygenases in glomerular injury, G.M. Nassar and K.F. Badr; multiple roles for platelet-derived growth factor in renal disease, J. Floege and R.J. Johnson; endothelin in the progressive renal disease of glomerulopathies, A. Benigni and G. Remuzzi; mediators of hyperglycemia and the pathogenesis of matrix accumulation in diabetic renal disease, F.N. Ziyadeh; cellular mechanisms of tubule hypertrophy and hyperplasia in renal injury, G. Wolf; the pathogenesis of tubulointerstitial disease associated with glomerulonephritis - the glomerular cytokine theory, R. Pichler et al; angiotensin II-mediated renal injury, R.C. Harris and M. Martinez-Maldonado; tumour necrosis factor in renal injury, L. Baud and R. Ardaillou; role of intrarenal endothelin in the generation and maintenance of hypertension, B.A. Markewitz and D.E. Kohan; renal tubule cell repair following acute renal injury, H.D. Humes et al.