1. Predicting Type 1 diabetes (P. Bingley, E. Bonifacio, E.A.M. Gale). 2. Environmental factors and Type 1 diabetes - Is the secretory granule the target? (M.A. Myers). 3. Maturity-onset diabetes of the young (T.M. Frayling, A.T. Hattersley). 4. Gestational diabetes mellitus and future Type 2 diabetes (M.R. Druce, A. Dornhorst). 5. Diabetes in China and Chinese populations (C.S. Cockram, J.C.N. Chan). 6. Insulin dependent intracellular traffic of glucose transporters (L.J. Foster, Z. Khayat, A. Klip). 7. The role of free fatty acids in muscle insulin resistance (E.W. Kraegen, G.J. Cooney). 8. Tumour necrosis factor alpha (E.C. Ledgerwood, J.B. Prins). 9. The role of beta adrenergic signalling in the regulation of fat and energy metabolism (Y.T. Kruszynska, J.P. Frias). 10 .Regulation of appetite (P.S. Widdowson, G. Williams). 11. Insulin-like growth factor I treatment for diabetes mellitus (D.B. Dunger, C.L. Acerini). 12. Insulin analogues (T.R. Pieber, G.A. Brunner, A. Siebenhofer). 13. The amylin analogue pramlintide: mechanism of actions and possible therapeutic implications (O. Schmitz). 14. Diabetes and smoking (P.Van Combrugge). 15. Insulin resistance and cardiovascular disease (B.V. Howard, S. Gray). 16. Hyperglycaemia as a risk factor for cardiovascular disease (M.Laakso). 17. Prevention of visual loss in diabetic retinopathy (E.M. Kohner). 18. Diabetes education in childhood (V. Barron, M. Silink). 19. Mechanism of diabetic embryopathy (U.J. Eriksson. J. Cederberg, P. Wentzel). Subject Index.