Introduction: Marianne Manchester and Nicole F. Steinmetz.- Chapter 1: Chemical modification of viruses and virus-like particles by Erica Strable and M.G. Finn.- Chapter 2: Structure-based Engineering of an Icosahedral Virus for Nano-medicine and -technology by Nicole F. Steinmetz, Tianwei Lin, George P. Lomonossoff, and John E. Johnson.- Chapter 3: Hybrid Assembly of CPMV Viruses and Surface Characteristics of Different Mutants by Nathaniel G. Portney, Giuseppe Destito, Marianne Manchester, and Mihrimah Ozkan.-Chapter 4: A Library of Protein Cage Architectures as Nanomaterials by Michelle L. Flenniken, Masaki Uchida, Lars O. Liepold, Sebyung Kang, Mark J. Young, and Trevor Douglas.- Chapter 5: Biomedical nanotechnology using virus-based nanoparticles by Giuseppe Destito, Anette Schneemann, and Marianne Manchester.- Chapter 6: Tumor targeting using canine parvovirus nanoparticles by Pratik Singh.- Subject index.