Mass Spectrometry: Techniques for the Structural Characterization of Glycans presents new methods for conducting detailed carbohydrate qualitative analysis-arming analytical chemists, pharmaceutical scientists, and food scientists with a quick reference that will allow them to determine the structures of carbohydrates molecules.
As there is a need in the scientific community for content specific to structural determination and analysis of new glycoprotein drug, and because structure-activity analysis requires a structural determination of the N- and O-linked oligosaccharides linked to glycol-proteins, this book provides the relevant research that are necessary for advances and new outcomes in this area of study.
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Verlagsort
Zielgruppe
Maße
Höhe: 229 mm
Breite: 152 mm
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ISBN-13
978-0-12-804129-1 (9780128041291)
Copyright in bibliographic data and cover images is held by Nielsen Book Services Limited or by the publishers or by their respective licensors: all rights reserved.
Schweitzer Klassifikation
Mike Madson is CEO and Senior Research Scientist of BioLogistics, LLC, Iowa, USA
Autor*in
BioLogistics, LLC, Iowa, USA
* Introduction* Monosaccharide Composition Analysis* Elemental Analysis of MS Ions* Derivatization Techniques* Hydride Addition to Sulfate and phosphate- Chemistry* InstrumentationMALDI-TOF MSAPI 2000 MSICP ESI TOF MS* Hydride Insertion Addition Reaction for the Derivatization of Phosphorylated or Sulfated Glycans and the Discernment of Phosphate versus Sulfate Esters* Ester Substitution MS MethodThe Protocol for the Hydride Addition to the ethanol extract of banana fruitExample of MS2on Hydride added to the ethanol Extract of Banana Fruit Glycan* Glycan Isolation Methods* Other Glycan isolation Methods* Monosaccharide AnalysisAcid Hydrolysis* Mass Spectral Carbohydrate Structure Determination MethodMSMS/MS (MS2)MSnProposing Initial Structure Refining Methods for Determining Exact Mass StructureMS Instrumentation Requirements for Discovering Whole Molecule IonsDerivatization Method and Sulfate/Phosphate Discernment Method* References
