This book offers a comprehensive look at the science of gene expression and regulation. Focusing on topics such as actions of nuclear receptors, RNA processing, and DNA methylation and imprinting, Gene Expression and Regulation is edited by a leading biologist and includes contributions by experts in the field. The focus is on scientific concepts and issues, rather than specific organisms or experimental approaches.
Sprache
Verlagsort
Zielgruppe
Für Beruf und Forschung
Professional/practitioner
Illustrationen
91
45 s/w Abbildungen, 91 farbige Abbildungen
45 black & white illustrations, 91 colour illustrations
Maße
Höhe: 27.9 cm
Breite: 21.6 cm
ISBN-13
978-0-387-33208-6 (9780387332086)
Schweitzer Klassifikation
Jun Ma, PhD, is an Associate Professor, Division of Developmental Biology, Cincinnati Children's Hospital Research Foundation, University of Cincinnati College of Medicine, Cincinnati, Ohio, USA.
Section I: The History * 1. Transcription--Then and Now; * Section II: The Machinery * 2. GTFs, PIC Information; * 3. RNA Polymerase Holoenzyme; * 4. Mediators/Adaptors, TBP and TAFs; * 5. Chromation and Chromation Remodeling; * 6. HATs and HDACs; * 7. Core Promoter Elements; * Section III: The Regulators * 8. Activators and Activation Mechanisms; * 9. Repressors and Repression Mechanisms; * 10. STATs; * 11. Smads; * 12. RB-E2F; * 13. AP-1; * 14. HIV Tat; * 15. p53; * 16. Actions of Nuclear Receptors; * 17. NFAT; * 18. Homeodomain Proteins; * 19. NFkB/Rel; * 20. ATFs; * Section IV: The Genome * 21. Insulators and Chromatin Boundaries; * 22. Heterochromatin and X Inactivation; * 23. DNA Methylation and Imprinting; * 24. Genomics and Transcription; * 25. DNA Synthesis/Integrity and Transcription; * 26. Cell Death and Transcription; * Section V: Special Topics * 27. RNA Processing; * 28. DNA Topology and Transcription; * 29. miRNA and RNAi; * 30. Developmental Signals and Transcription; * 31. Gene Expression in Plants; * 32. Bacterial Gene Regulation; * 33. Gene Therapy; * 34. Transcription Factor Dynamics; * 35. Actin, Myosin, and ARPs in Transcription
