This is a high-level clinical research text updating current knowledge about the documented effects of sex steroids on the cardiovascular system. It contains nineteen chapters covering the full range of oral contraceptive issues of greatest concern to today's practitioners and researchers in gynecology, obstetrics, reproductive medicine, cardiology, and clinical pharmacology. Key contributions contain the very latest information about the relationship between oral contraceptives and coronary heart disease, hormone replacement therapy (HRT), effects of oral contraceptives on lipid metabolism and carbohydrate metabolism, adverse effects of estrogen treatment, and the relationships between oral contraceptives and hemostasis and breast cancer. Includes detailed bibliographic references and a thorough index.
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ISBN-13
978-1-85070-956-5 (9781850709565)
Copyright in bibliographic data is held by Nielsen Book Services Limited or its licensors: all rights reserved.
Schweitzer Klassifikation
Ovarian hormones and vascular function. Cardiovascular disease and HRT - epidemiological data. Oral contraceptives and coronary heart disease. Testosterone and the cardiovascular system in males. Effect of mammalian estrogens and phytoestrogens on the vascular system. Evidence for cardiovascular effects of sexual steroids in rabbits - a sex hormone receptor mediated mechanism? Effects of estrogens alone or combined with progestrogens on lipid and lipoprotein metabolism. Effects of oral estradiol alone or combined with progestogen on carbohydrate metabolism in postmenopausal women. Adverse effects of estrogen treatment: natural vs. synthetic estrogens. Hemodynamic changes in the menstrual cycle. Critical analysis of different methods of measuring blood flow. Peripheral arterial blood flow and estrogen replacement. Effects of HRT on Duplexsonographic quantification of carotid atherosclerosis in postmenopausal women. Non-lipid mechanisms of estrogen effects on the coronary vasculat ure. Effects of estradiol and its metabolites on the contractility of human arteries. In vitro and in vivo investigations of possible effects of sexual steroids on the vasculatures. Role of estradiol level in coronary heart disease in premenopausal women. Risk of breast cancer developed during estrogen therapy. Index.
