The discovery of a bone-inducing principle was paradoxically the result of a failed experiment intended to recalcify cortical bone. Using demineralized rabbit and rat bone matrix which was then implanted in muscle pouches, surprised researchers noticed that new cartilege and bone developed on or around the bone matrix surfaces. BMP is the generic name for the proteins extracted from bone matrix and the ability to extract these proteins has obvious research and clinical implications. This book covers research in bone morphogenetic proteins conducted from 1965 through 1995. Chapters range from immune response to regeneration of bone defect and focus on clinical treatment problems. Special reference is given to reconstructive repair, starting with clinical treatment of bone deficiencies.
Reihe
Sprache
Verlagsort
Verlagsgruppe
Elsevier Science Publishing Co Inc
Zielgruppe
Für höhere Schule und Studium
Für Beruf und Forschung
Gewicht
ISBN-13
978-0-12-450745-6 (9780124507456)
Copyright in bibliographic data is held by Nielsen Book Services Limited or its licensors: all rights reserved.
Schweitzer Klassifikation
Thirty Years of Bone Morphogenetic Protein Research. Bone Morphogenetic Protein in Biology and Medicine. Biochemical Extraction, Purification and Characterization of Native Bone Morphogenetic Protein. Recombinant Bone Morphogenetic Proteins: Cloning and Molecular Structures. Bone Induction and Immune Occurrence in Bone Morphogenetic Protein Implantation. Target Cells and Receptors for Bone Morphogenetic Protein. Bone Inducivity of Malignant Bone Neoplasms and Cultured Osteosarcoma Cells. Bone Morphogenetic Protein Derived from Osteosarcoma Cells. Bone Morphogenetic Protein Derived from Osteosarcoma. Osteoinductive Difference Between Purified Bovine and Recombinant Human Bone Morphogenetic Protein. Bone Morphogenetic Protein and Transforming Growth Factor-B. Searching for a Novel Carrier for Bioactive Delivery of Bone Morphogenetic Protein. The Generation of Bone in Primates By Bone Morphogenetic Proteins. Bone Morphogenetic Proteins and Derivatives Potentiate Healing of Segmental Diaphyseal Bone Defects and Non-Union of Fractures. Bone Morphogenetic Proteins and Dentinogenesis. Induction of Cementogenesis and Periodontal Ligament Regeneration By Bone Morphogenetic Proteins and Dentinogenesis. Induction of Cementogenesis and Periodontal Ligament Regeneration By Bone Morphogenetic Proteins. Demineralized Bone Matrix Inductive Graft. Purified Bovine Bone Morphogenetic Protein for Clinical Use in Difficult Conditions of Cranio-Maxillofacial Surgery. Experiences Using Native Allogenic and Xenogeneic Bone Morphogenetic Protein in Curing Bone Disturbances in Domestic Dogs. Clinical Use of Recombinant Human Bone Morphogenetic Protein-2 Antibody in Diagnosis of Osteigenic Lesions.
