In recent years C-glycoside chemistry has been one of the main topics in carbohydrate chemistry, not only because of the synthetic challenges posed, but also because C-glycosides have the potential to serve as carbohydrate analogues resistant to metabolic processes. Consequently, this class of compounds is currently receiving much interest as a potential source of therapeutic agents for clinical use. This book provides a broad coverage of the various synthetic methods available for the preparation of C-glycosides, and illustrates the interesting breadth of connections between carbohydrate chemistry and modern general synthetic organic chemistry by including topics such as transition-metal catalysis, radical chemistry, cycloaddition and rearrangement processes. In addition, in the final chapter of the book, the syntheses of C-di and trisaccharides reported through 1994 are reviewed. This well organised account of the synthetic chemistry in this field will prove to be very valuable to a wide range of researchers and advanced students, both as an introduction to the topic and for reference.
Rezensionen / Stimmen
"This is a monumental work that provides essentially comprehensive coverage of C-gylcosides. This book shows various synthetic methods available for the preparation of C-glycosides, and illustrates the interesting breadth of connections between carbohydrate chemistry and modern general synthetic organic chemistry.... It should become an important companion for both graduate students and senior researchers in the field." --Heterocycles
"The book discusses the chemistry of C-glycosides in eight chapters.... The following reaction types are covered: electrophilic substitutions, nucleophilic substitutions, transition metal mediated C-glycosylations, anomeric radicals, rearrangements and cycloadditions, and sugar ring formations.... In summary, the book is well presented and gives a comprehensive review of the subject. It should be of interest to a wide audience." --Chemistry and Industry
"This book, like others in the Tetrahedron Organic Chemistry Series, represents a timely review of the rapidly burgeoning field in carbohydrate chemistry. The emphasis of this book is on the synthetic perspective of C-glycosides.... The book is concisely written and the schemes are neatly drawn. Graduate students and researchers interested in organic synthesis related to carbohydrates will find this useful, as the book serves an excellent introductory overview of the subject it covers.... This reviewer recommends this book enthusiastically." --Synthesis
Reihe
Sprache
Verlagsort
Verlagsgruppe
Elsevier Science & Technology
Zielgruppe
Für höhere Schule und Studium
Für Beruf und Forschung
Maße
Höhe: 254 mm
Breite: 178 mm
ISBN-13
978-0-08-042080-6 (9780080420806)
Copyright in bibliographic data is held by Nielsen Book Services Limited or its licensors: all rights reserved.
Schweitzer Klassifikation
Dr. Tang is a professor at the Department of Food Science and Technology of South China University of Technology. He holds a Bachelor of Science degree in Food Science and Technology from Zhejiang University of Technology, China and obtained a Master in Food Engineering from Wuxi University of Light Industry, and a doctorate (Ph.D.) in Food Science from South China University of Technology. Professor Tang has conducted almost 20 years of research in the areas including food science, food colloids, functional foods and protein-based materials, especially those related to plant proteins. His recent research interests include structure and functionality of plant protein chemistry, development and novel applications of plant protein-stabilized emulsions, and nanoencapsulation of bioactives. In these areas, he has published more than 140 papers and edited two books. Currently he serves as an associate editor of several journals, including Food Research International (Elsevier) and Journal of Integrative Agriculture (Elsevier).
Herausgeber*in
Glycomed Inc., California, USA
Professor, Department of Food Science and Technology, South China University of Technology, Guangzhou South China
1. Electrophilic Substitutions
2. Nucleophilic Sugar Substitutions
3. Transition Metal Mediated C-Glycosidations
4. Anomeric Radicals
5. Rearrangements and Cycloadditions
6. Sugar Ring Formations
7. Syntheses of C-Di and Trisaccharides
