The Biological Role of Proteinases and Their Inhibitors in Skin: 1st

Preface. List of contributors. Lysosomal thiol proteinases and their endogenous inhibitors in rat skin. Physiological inhibitors of the human lysosomal cysteine proteinases. Localization of cathepsins H and L and their inhibitors in stratified epithelia and lymphatic tissue. Structure and function of epidermal proteases and their inhibitors. Recent advances in studies on tissue-type plasminogen activator. Proteases, angiogenesis, and invasion. Plasminogen activator of human epidermis: characterization of the enzymes and modulation by anti-cell surface antibodies. Characterization of high-molecular-weight plasminogen activator produced by cultured human epidermal cells. Calpain and calpastatin: biochemical and immunohistochemical distribution studies in various tissues. Biochemical and immunohistochemical studies of calpain in human skin. Calcium-activated neutral protease is a chimeric protein with distinct functional domains. The role of leukocyte cathepsin G and chymase in inflammation. Human skin tryptase. Murine leprosy: an animal model to investigate the proteinase-proteinase inhibitor regulation system in inflammation. Keratin-hydrolyzing enzyme in psoriatic epidermis. The biological role of keratinolytic proteinase and its inhibitor on the growth of Candida albicans. The physiological role of plasma proteinase inhibitors. Low-molecular-weight protease inhibitors produced by microorganisms. Isolation and characterization of a low-molecular-weight (2,200 Mr.) proteinase inhibitor of human epidermis. The biologial role of proteinases and their inhibitors in the pathogenesis of epidermolysis bullosa-recessive dystrophic and simplex types. Reverse regulation of *g-glutamyl transpeptidase (*g-GTP) in cultured melanotic B-16 melanoma cells by L-glutamine. A humoral factor affecting basophils in contact sensitivity. Index.