Part 1 Steroid kinetics and metabolism: steroid hormone transport through the blood-brain barrier - methods and concepts, W.M. Pardridge; enhanced delivery of steroids to the brain using a redox-based chemical delivery system, J.W. Simpkins and N. Bodor; neurosteroids - biosyntheisis and function, P. Robel and E.-E. Baulieu; cytochrome P450 enzymes in brain, M. Warner et al; methods for estimating 11b-hydroxysteroid dehydrogenase activity, Z. Krozowski. Part 2 Steroid receptors: steroid hormone binding to intracellular receptors - "in vitro" and "in vivo" studies, A.D. Van Harst and T.F. Szuran; steroid hormone binding to membrane receptors, M. Orchinik and T.F. Murray; "in vitro" autoradiography for steroid receptors, N.J. MacLusky et al; immunocytochemical studies on glucocorticoid receptor, A. Cintra et al; confocal scanning laser microscopy of steroid receptors in brain, B. van Steensel et al; ultrastructural aspects of steroid receptor localization - an immunocytochemical perspective, Z. Liposits and I. Kallo; hybridization studies of adrenocorticosteroid receptors in central nervous system, J.P. Herman et al; detection and characterization of epalon receptors - novel recognition sites for neuroactive steroids that modulate the GABAA receptor complex, L.D. McCauley and K.W. Gee; mutation analysis of steroid hormone receptors, M. Karl et al. Part 3 Molecular effects of steroids: protein-DNA binding assay for analysis of steroid-sensitive neurons in mammalian brain, Y.-S. Zhu and D.W. Pfaff; gene transfection studies using recombinant steroid receptors, K. Damm; regulation of neuropeptide genes - determination of responsiveness to steroids and identification of receptors in brain nuclei, J.J. Cox et al; cloning of steroid-responsive mRNAs by differential hybridization, N.R. Nichols et al; molecular correlates of corticosterone action in hippocampal subregions, S.M. Nair and J.H. Eberwine; glucocorticoid-determined protein synthesis, L.A. Dokas; use of antisense oligodeoxynucleotides to block gene expression in the central nervous system, M.M. McCarthy. Part 4 Cellular effects of steroids: steroid regulation of neuronotrophic activity - primary microcultures of midbrain raphe and hippocampus, E.C. Azmitia and X.-P. Hou; central glucocorticoid receptors and neuronal plasticity, K. Fuxe et al; steroid action on neuronal structure, C.S. Woolley and E. Gould; electron microscopic double and triple labelling immunocytochemistry in elucidation of synaptological interactions between ovarian steroid-sensitive neurons and circuits, C. Leranth et al; gene-mediated steroid control of neuron activity, M. Joels; electrophysiological studies of neurosteroid modulation of [gamma]-aminobutyric acid type a receptor, C. Hill-Venning et al; "in vitro" approaches to studying glucocorticoid effects on gene expression in neurons and glia, M.C. Bohn. Part 5 Steroid effects on integrated systems. (Part contents).