Evolution of Atopic Dermatitis in the 21st Century

Introduction: History and definition.- Epidemiology: Epidemiology of Childhood AD in Japan.- Epidemiology of Childhood AD in Asican countries.- Retrospective cohort study in Adlescent AD.- Genetics: GWAS study in Japanese AD.- Etiopathology of AD from Japanese studies: Non-immunological aspect:Barrier (Filaggrin to tight junction).- Immunological aspect: Th2/Mast cell/basophil/Eosinophil.- Immunological aspect: DC/ILC.- Cytokine network.- Itch and psychiatric aspect.- Sweat.- Microbiom.- Stress.- Animal model.- Classification: Classification (Intrinsic & Extrinsic type).- Clinical manifestations: Infantile and childhood AD.- Senile AD.- Differential Diagnosis .- Diagnosis: Diagnosis and Japanese guideline.- Management: Drug therpay: Ointment.- Drug therpay: Systemic.- Skin care and intervention.- Approach for gaggravating factors.- WPAI.- New and future therapies.- Complications: Pollenopsis.- Food Allergy.- Clinical questions : Clinical questions .