The past decade has witnessed the emergence of verocytotoxin (VT)-producing Escherichia coli (VTEC), particularly serotype 0157:H7, as major food-borne pathogens of humans. Of particular public health concern are the serious complications of VTEC infection. This volume contains a selection of papers that were presented at the above mentioned symposium and workshop, from June 27th to 30th, 1994. The participants of VTEC '94, from 25 different countries, represented diverse areas of interest including clinical and public health microbiology, internal medicine, pediatrics, veterinary microbiology, microbial pathogenesis, and the food industry. This, together with the participation of leading experts in the field enabled VTEC '94 to realise its mission of promoting a multidisciplinary state-of-the-art meeting on the topic of VTEC infection.
The past decade has witnessed the emergence of verocytotoxin (VT)-producing Escherichia coli (VTEC), particularly serotype 0157:H7, as major food-borne pathogens of humans. Of particular public health concern are the serious complications of VTEC infection. This volume contains a selection of papers that were presented at the above mentioned symposium and workshop, from June 27th to 30th, 1994. The participants of VTEC '94, from 25 different countries, represented diverse areas of interest including clinical and public health microbiology, internal medicine, pediatrics, veterinary microbiology, microbial pathogenesis, and the food industry. This, together with the participation of leading experts in the field enabled VTEC '94 to realise its mission of promoting a multidisciplinary state-of-the-art meeting on the topic of VTEC infection.
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Elsevier Science & Technology
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Für höhere Schule und Studium
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ISBN-13
978-0-444-81840-9 (9780444818409)
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Schweitzer Klassifikation
Part 1 Public health, epidemiology, food safety, and laboratory diagnosis: summary - public health; epidemiology; food safety; laboratory diagnosis, I.K. Wachsmuth; three years PCR screening for VTEC in human stools in Brussels, D. Pierard et al; the role of enterohaemorrhagic E. Coli serotypes other than 0157:H7 as causes of disease, P.N. Goldwater and K.A. Bettelheim; detection of verocytotoxin-producing escherichia coli in meat in Belgium, D. Pierard et al; developments of a clinically useful diagnostic enzymes immunoassay for enterohemorrhagic escherichia coli infection, D.W.K. Acheson et al. Part 2 Toxin structure, function, and mechanisms of interaction with eukaryotic cells: overview of session 2 - toxin structure-function, receptors, cell biology, S.B. Calderwood; identification of a candidate gal alpha-4 binding pocket in the B subunit of escherichia coli verotoxin 1, D. Bast et al; the role of monocytes in the pathogenesis of the haemolytic uraemic syndrome (HUS), P.A. van Setten et al. Part 3 Virulence factors and mechanisms of pathogenicity of VTEC including mechanisms of mucosal colonization and systemic VT-induced injury: intracellular changes in 'attaching and effacing' adhesion, S. Knutton et al; effects of sugars on the adhesion of vero cytotoxin-producing escherichia coli of serogroups 0157 and 0111, Y. Nishikawa et al; regulation of shiga-like toxin-II production by the nucleoid-associated DNA-binding protein H-NS, I. Muhldorfer et al. Part 4 Clinical and pathophysiological aspects of the hemolytic uremic syndrome (HUS) including endothelial cell biology, inflammatory mediators, and immunity: a critical review of haemolytic uraemic syndrome pathophysiology, C.M. Taylor; verocytotoxin (VT1) induces the expression of heat shock protein 70 (hsp 70) in vero and human endothelial cells, I.D. Chant et al; serum and urinary cytokines in childhood haemolytic uremic syndrome and thrombotic thrombocytopenic purpura, D. Karpman et al. (Part Contents).
