In this book, Harold Kalter challenges the belief that the babies of women with insulin-dependent diabetes are congenitally malformed more often than babies of nondiabetic women He traces the origin of this idea to a survey of births to diabetic women in a Danish hospital reported in 1964 and follows the trail of literature to the present Kalter points out the two errors most responsible for the faulty theory, a loose definition of the term malformation and the use of misrepresentative studies Specifically, Kalter argues that the use of patients who are cared for in hospital diabetes departments and specialized diabetes clinics does not represent the entire population of diabetic women accurately Building on these weaknesses, Kalter argues that congenital malformations do not occur, and probably never have occurred, more frequently in the children of diabetic women
Rezensionen / Stimmen
'This monograph attacks the widely held belief that maternal diabetes is teratogenic, i.e., that it disturbs the development of the embryo. Rarely has an iconoclastic treatment of a subject been so thoroughly researched and documented.' - F. Clarke Fraser, McGill University, Quebec
'The book will be an important contribution to the field and, in fact, may be the most important book ever written on the subject of congenital malformations and diabetes mellitus.' - Dan C. Moore, Madigan Army Medical Center, Tacoma, Washington
Sprache
Verlagsort
Verlagsgruppe
Zielgruppe
Für höhere Schule und Studium
Für Beruf und Forschung
Gewicht
ISBN-13
978-90-5702-617-1 (9789057026171)
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Schweitzer Klassifikation
Professor Emeritus of Pediatrics
1. The Framework of Diabetes 2. The Early Years 3. Spontaneous Abortion 4. Perinatal Mortality 5. Prediabetes 6. Gestational Diabetes 7. Classification of Diabetes in Pregnancy 8. Congenital Malformation-What, When, Where 9. Case Reports of Maternal Diabetes and Malformation 10. Maternal Diabetes and Malformations 11. Studies by Diabetes Centers 12. Broad-Scale Studies 13. Population-Based Studies 14. Specific Congenital Malformations 15. Preventing Congenital Malformations 16. Early and Late Studies: Prenatal and Follow-up 17. Diabetic Pregnancy in Animals: I 18. Diabetic Pregnancy in Animals: II 19. Is Diabetes Teratogenic?