It was Oscar Wilde who defined the tragedy of old age by saying that " . . . as soon as you are old enough to know better, you don't know anything at all. " As improvements in the quality of health care bring about longer life, our attention has turned from the prolonging of life to the maintenance of involvement in life. In developed nations, a full 100% increase in the ranks of the elderly has appeared and with the benefits of this prolongation have come new and greater needs of the elderly cohort. Our interest is in those processes that may lead to dementia among the elderly, for in dementia we see a thief that robs victims of their memories and their place in life. This text was conceived and developed from an international con ference on neurodevelopment, aging, and cognition; the purpose of this few days a group of experts in these conference was to bring together for a fields from around the world to generate a dialog on common themes and unresolved problems. Our hope was that by keeping the meeting small and informal, we could break through barriers of terminology unique to the areas of developmental neurobiology, neuroscience, cognitive sci ence, and clinical medicine, and have a meaningful discussion on pro cesses that affect the biological integrity and cognitive performance of the aging nervous system.
Auflage
Sprache
Verlagsort
Zielgruppe
Für höhere Schule und Studium
Für Beruf und Forschung
Research
Illustrationen
Maße
Gewicht
ISBN-13
978-0-8176-3599-2 (9780817635992)
DOI
10.1007/978-1-4684-6805-2
Schweitzer Klassifikation
I. Neurodevelopment.- Developmental Reorganization of the Human Association Cortex during Perinatal and Postnatal Life.- Prenatal Monoaminergic Innervation of the Cerebral Cortex: Differences between Rodents and Primates.- Ontogenetic Development and Decline of Memory Functions in Nonhuman Primates.- Anoxia and Memory Processes.- Brain before Cognition: EEG Maturation in Preterm Infants.- Mechanisms of Asymmetrical Development of the Human CNS.- Neuroanatomical Bases of Hemispheric Functional Specialization in the Human Brain: Developmental Factors.- II Neuroscience.- Development and Aging in Down's Syndrome.- Alzheimer's Disease and the Cerebral Amyloidoses.- Evolution of Cholinergic Cortical Innervation after nbM-Lesioning (An Experimental Alzheimer Model).- Neurodegenerative Changes in Aging and Dementia: A Comparison of Alzheimer and Lewy Body Type Pathology.- Cortical Morphological Changes in Dementia.- Neuroendocrine Changes in Aging and Alzheimer's Disease.- III. Cognitive Science.- Developing a Memory "Thermometer": A Theoretical Framework and Initial Results.- Biological Bases of Specific Language Impairment (Developmental Aphasia).- Brain/Cognition Relationships: Interpreting the Effects of Focal Brain Damage.- A Spreading Activation Model of Age-related Deficits in Cognition.- Memory Changes in Aging.- IV. Clinical Applications.- CT, MRI, and PET Studies of Hippocampal Pathology in Alzheimer's Disease.- Is Alzheimer's Dementia a Treatable Disease?.- Dementia of the Alzheimer Type Recapitulates Ontogeny Inversely on Specific Ordinal and Temporal Parameters.- Psychopharmacological Aspects of Antidementia Agents.- Pharmacological Treatment of Alzheimer's Dementia: A Review.
