The Peptidergic Neuron

Name: The Peptidergic Neuron | Proceedings of the 11th International Symposium on Neurosecretion, Vrije Universiteit, Amsterdam, The Netherlands, 10-14 June 1991
Price: 185.92 EUR
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ISBN: 978-0-444-81457-9

Proceedings of the 11th International Symposium on Neurosecretion, Vrije Universiteit, Amsterdam, The Netherlands, 10-14 June 1991

J. Joose etc.(Herausgeber*in)

Elsevier (Verlag)

Erschienen im September 1992

Buch

Hardcover

426 Seiten

978-0-444-81457-9 (ISBN)

185,92 €inkl. 7% MwSt.

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Beschreibung

The exploration of the phenomenon of neurosecretion has developed from a morphological interest in neurons that produce hormones, through the discovery of the chemical nature of the secretion products and the diversity of actions of these messengers, towards the multidisciplinary study of a special class of neuronal messengers, the neuropeptides. This volume reflects the increase in knowledge of the peptidergic neuron and helps improve the contacts between those interested in this subject. Three aspects receive special attention: the overwhelming uniformity in the basic mechanisms of neuropeptide synthesis and secretion across animal species of different phyla, organismic biology of peptidergic systems and elucidation of the molecular structure and genomic coding of neuropeptides in insects. This excellent member of the well known Progress in Brain Research series stimulates closer cooperation between investigators studying representatives of different animal groups and paints a clear picture of developments in this exciting corner of scientific research.

The exploration of the phenomenon of neurosecretion has developed from a morphological interest in neurons that produce hormones, through the discovery of the chemical nature of the secretion products and the diversity of actions of these messengers, towards the multidisciplinary study of a special class of neuronal messengers, the neuropeptides. This volume reflects the increase in knowledge of the peptidergic neuron and helps improve the contacts between those interested in this subject. Three aspects receive special attention: the overwhelming uniformity in the basic mechanisms of neuropeptide synthesis and secretion across animal species of different phyla, organismic biology of peptidergic systems and elucidation of the molecular structure and genomic coding of neuropeptides in insects. This excellent member of the well known Progress in Brain Research series stimulates closer cooperation between investigators studying representatives of different animal groups and paints a clear picture of developments in this exciting corner of scientific research.

Weitere Details

Inhalt

E. Scharrer - W. Bargmann Memorial Lecture. 1. Brain secretory peptides of the silkmoth Bombyx mori : Prothoracicotropic hormone and bombyxin (H. Ishizaki and A. Suziki). Evolutionary aspects of neuropeptides and their genes. 2. Structure and evolution of insulin and insulin-like growth factors in chordates (S.J. Chan, S. Nagamatsu, Q.-P. Cao and D.F. Steiner). 3. Relationships among the FMRFamide-like peptides (M.J. Greenberg and D.A. Price). 4. Molecular evolution of neurohypophysial hormone precursors (A. Urano, S. Hyodo and M. Suzuki). 5. A vasopressin-related peptide in the mollusc Lymnaea stagnalis : peptide structure, prohormone organization, evolutionary and functional aspects of Lymnaea conopressin (R.E. van Kesteren, A.B. Smit, N.D. de With, J. van Minnen, R.W. Dirks, R.C. van der Schors and J. Joosse). Molecular biology of neuropeptides - Regulation of neuropeptide genes. 6. Models for the study of cell-specific neuropeptide gene expression (S. Wray and H. Gainer). 7. Neuropeptide gene expression in transgenic animals (D. Murphy, H.-L. Ang, Q. Zeng, M.-Y. Ho, J. Funkhauser and D. Carter). 8. Spatiotemporal patterns of transcription factor gene expression accompanying the development and plasticity of cell phenotypes in the neuroendocrine system (L.W. Swanson). 9. Alternative mRNA splicing in the nervous system (J.F. Burke, K.E. Bright, E. Kellet, P.R. Benjamin and S.E. Saunders). 10. Regulation of vasopressin and oxytocin gene expression by estrogen and thyroid hormones (R.A.H. Adan and J.P.H. Burbach). 11. The peptidergic nervous system of coelenterates (C.J.P. Grimmelikhuijzen, D. Darmer, C. Schmutzler, K. Carstensen, H.-P. Nothacker, R.K. Reinscheid, K.L. Rinehart and I.D. McFarlane). 12. Mutant vasopressin precursor producing cells of the homozygous Brattleboro rat as a model for co-expression of neuropeptides (F.W. van Leeuwen). 13. Purification of a new neuropeptide from locust corpus cardiacum which influences ileal transport (N. Audsley, C. McIntosh and J.E. Phillips). Differentiation and development of peptidergic neurons. 14. Molecular genetic analysis of the FMRF-amide-related neuropeptides in Drosophila (P.H. Taghert, M.A. O'Brien, L.E. Schneider and M.S. Roberts). 15. Somatostatin: a putative neurotrophic factor with pleiotropic activity in the rat central nervous system (P. Leroux, B.J. Gonzalez, C. Bodenant, C. Bucharles and H. Vaudry). 16. Topographical displacement of neuropeptide-producing nuclei as an indicator of evolutionary brain development (S. Blahser). Receptors and peptide analogues. 17. Molecular biology of G-protein-coupled receptors (G.J.M. Martens). 18. Strategies in the development of peptide antagonists (V.J. Hruby). 19. Antibodies to neuropeptides as alternatives for peptide receptor antagonists in studies on the physiological actions of neuropeptides (J.W.A.M. van Oers, C. van Bree, A. White and F.J.H. Tilders). Processing, transport and release. 20.

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