Periodontal diseases and dental caries are almost universally prevalent across the world, and oral cancer, the commonest cause of cancer in some developing countries, is a growing problem also in industrial populations. Nevertheless, severe oral disease exists in only a minority of any population, and the three volumes forming Risk Markers for Oral Diseases set out to characterize these at-risk groups and define markers by which they may be identified. Reviewing epidemiological, clinical and laboratory data, these volumes point the way towards improved diagnostic and prognostic testing, an exciting and rapidly expanding aspect of dentistry. This volume discusses in detail the distribution of periodontal diseases in the populations of industrialized and non-industrialized countries. It considers the characteristics of high-risk groups and individuals within these populations, analysing subject-based risk factors and clinical markers. Particular consideration is given to new methods for microbial screening and to the measurement of local and systemic immune responses in the host, which may lead to the development of biologically based diagnostic tests. Risk Markers for Oral Diseases represents a landmark in the reorientation of contemporary dentistry towards new goals. This volume and its companions are therefore essential works of reference for all dental professionals.
Rezensionen / Stimmen
'This is a good read for those who wish to be kept up to date with this very topical field. It provides a great deal of information and comprehensive lists of references.' Eddie Gergely, Dental Practice
Sprache
Verlagsort
Zielgruppe
Illustrationen
11 Halftones, unspecified; 94 Line drawings, unspecified
Maße
Höhe: 234 mm
Breite: 152 mm
Dicke: 28 mm
Gewicht
ISBN-13
978-0-521-38566-4 (9780521385664)
Copyright in bibliographic data is held by Nielsen Book Services Limited or its licensors: all rights reserved.
Schweitzer Klassifikation
Herausgeber*in
Nuffield Research Professor of Dental Sciences, Royal College of Surgeons of England, and Honorary Director, Medical Research Council Dental Research Unit, The London Hospital Medical College
1. Introduction: current concepts of the nature and natural history of periodontal diseases and the need for disease markers; Part I. Evidence for the Existence of High Risk Groups and Individuals: 2. The distribution of periodontal destruction in the populations of industrialized countries; 3. The distribution of periodontal destruction in the populations of non-industrialized countries: evidence for the existence of high risk groups and individuals; 4. Severe forms of periodontitis in children, juveniles and adults: worldwide prevalence; Part II. Methods for the Characterization of High Risk Groups and Individuals: 5. Unchanging, subject-based risk factors for destructive periodontitis: race, sex, genetic, congenital and childhood systemic diseases; 6. Changing subject-based risk factors for destructive periodontitis; 7. Clinical markers of active periodontal disease; 8. Immunological procedures for diagnosis and risk assessment in periodontal diseases; 9. Markers of periodontal disease susceptibility and activity derived from saliva; 10. Markers of periodontal disease susceptibility and activity derived from gingival crevicular fluid: specific vs. non-specific analyses; 11. Host-derived enzyme activities in gingival crevicular fluid as markers of periodontal disease susceptibility and activity: historical perspective, biological significance and clinical implications; 12. Prostaglandins and other eicanosoids in gingival crevicular fluid as markers of periodontal disease activity; 13. The connective tissues of the periodontium and their breakdown products in gingival crevicular fluid as markers of periodontal disease activity; 14. Do bacterial markers exist in subgingival plaque for predicting periodontal disease susceptibility?; 15. New methods for microbial screening in the diagnosis of periodontal infections: cultural, immunological, gene probes; Part III. Practical Applications and Implications: 16. Microbiologically based diagnostic tests for periodontitis. Considerations of sensitivity, specificity and accuracy; 17. The implications of the high risk strategy and of improved diagnostic methods for health screening and public health planning in periodontal diseases.
