Part I. How Great is the Risk?: 1. A global view of the epidemiology of oral cancer N. W. Johnson; Part II. Markers of the High Risk Patient: 2. Risk factors and risk markers for oral cancer in high incidence areas of the world D. K. Daftary, P. R. Murti, R. B. Bhonsle, P. C. Gupta, F. S. Mehta and J. J. Pindborg; 3. Risk factors and risk markers for oral cancer in low incidence areas of the world W. H. Binnie; 4. The Epstein-Barr virus in neoplasms of the head and neck G. De-The; 5. Evidence for infective agents in the aetiology of oral cancer C. Scully, S. S. Prime, M. F. Cox and N. J. Maitland; 6. Immune status in head and neck cancer, with special reference to cancer of the oral cavity S. G. Gangal and R. J. Tatake; Part III. Markers of the High Risk Lesion: 7. Clinical signs and symptoms of the high risk lesion M. Harris; 8. Structural indicators of the high risk lesion D. G. MacDonald and S. M. Saks; 9. Cytoplasmic markers of disturbed epithelial differentiation as markers of high risk lesions with special reference to cytokeratins P. R. Morgan, P. J. Shirlaw, E. B. Lane, I. M. Leigh and N. W. Johnson; 10. Cell surface carbohydrates in differentiation and malignant development of oral epithelium E. Dabelsteen, J. Reibel and H. Clausen; 11. Epithelial-mesenchymal interaction in tissue homeostasis and malignant transformation N. E. Fusenig, D. Breitkreutz, P. Boukamp, A. Bohnert and I. C. Mackenzie; 12. The biology of oncogenes and their role in malignant transformation J. K. Field; 13. Growth factors and their receptors as markers of the higher risk lesion, with special reference to epithelial growth factors A. A. Talacko, P. J. Shirlaw and N. W. Johnson; 14. Presence and expression of latent viruses in oral tissues N. J. Maitland, C. Lynas, T. Bromidge, I. Crane, S. R. Flint, M. F. Cox, S. S. Prime and C. Scully; 15. Human oral keratinocyte cultures and in vitro model systems for studying oral carcinogenesis S. E. Chang; Part IV. Implications of New and Existing Knowledge: 16. Implications for diagnosis, prognosis and patient management J. D. Langdon; 17. Public health aspects of oral cancer: implications for cancer prevention in the community J. J. Pindborg, D. K. Daftary, P. Gupta, M. B. Aghi, R. B. Bhonsle, P. R. Murti, F. S. Mehta and K. A. A. S. Warnakulasuriya; 18. Envoi: new knowledge concerning oral cancer and research priorities N. W. Johnson; Index.
