The means by which non-enveloped viruses penetrate cellular membranes during cell entry remain poorly defined. Recent findings indicate several members of this group share a common mechanism of membrane penetration in which the virus particle undergoes programmed conformational changes, leading to capsid disassembly and release of small membrane-interacting peptides.
A complete understanding of host cell entry by this minimal system will help elucidate the mechanisms of non-enveloped virus membrane penetration in general
Rezensionen / Stimmen
From the reviews:
"This book contains detailed, up-to-date descriptions of cellular entry mechanisms of non-enveloped viruses, such as ssRNA viruses (nodavirus, picornavirus, calicivirus), dsRNA viruses (orthoreovirus, rotavirus), ssDNA viruses (parvovirus) and dsDNA viruses (polyomavirus, adenovirus). . The book is strongly recommended to established virologists, molecular and structural biologists, and young scientists working in these areas." (Ulrich Desselberger, Microbiology Today, May, 2011)