The tail end of a gene, the 3' untranslated region (UTR), might seem insignificant, but it holds surprising power. This seemingly simple sequence acts as a decision point, influencing how much protein is made from a gene. Think of it as a dimmer switch on a gene's light.
The 3' UTR can be bound by regulatory molecules, acting like a dimmer switch that increases or decreases the mRNA's stability and translation into protein. Mutations or variations within the 3' UTR can disrupt this delicate control, leading to either overproduction or underproduction of crucial proteins.
This imbalance can have a significant impact on health. Diseases like cancer and neurodegenerative disorders have been linked to malfunctions in 3' UTR regulation. By understanding how the 3' UTR influences gene expression, scientists can potentially develop new therapies. Targeting this region could offer a way to fine-tune protein production and combat diseases caused by imbalances
Sprache
Verlagsort
Zielgruppe
Don't underestimate a gene's tail! The 3' UTR decides protein production, acting like a dimmer switch. Mutations here can cause imbalances linked to diseases like cancer. Understanding this control could lead to new therapies
Produkt-Hinweis
Maße
Höhe: 234 mm
Breite: 155 mm
Dicke: 11 mm
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ISBN-13
978-3-384-23460-5 (9783384234605)
Schweitzer Klassifikation
Autor*in
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