Systemic sclerosis is a diffuse connective tissue disorder characterized by fibrosis and vascular obliteration of small arteries and microvessels in the skin, gastrointestinal tract, lungs, heart and kidneys. Its cause is unknown and treatment is often frustrating, but there are some clues and some success is possible, particularly when treatment is initiated in the early stages of the disease. The purpose of this multi-contributor book is to facilitate an understanding of the underlying mechanisms of this unpleasant disease by describing the curent state of knowledge of the tissue changes that underly systemic sclerosis.
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Höhe: 250 mm
Breite: 190 mm
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ISBN-13
978-0-471-90846-3 (9780471908463)
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Schweitzer Klassifikation
Epidemiology; environmental and drug-induced scleroderma; genetic factors; humoral immunity in systemic scleroderma; genetic factors; cellular immunity in systemic sclerosis; connective tissue changes and their role in pathogenesis; models of scleroderma; skin changes; Raynaud's Phenomenon and Raynaud's Disease; gastrointestinal tract; pulmonary system; cardiac, renal, muscle, nerve and joint involvement; activity, assessment and outcome; endocrine function in scleroderma; treatment; localized scleroderma; childhood scleroderma; eosinophilic fascilitis; overlap syndromes.
