Section 1. Historical Overview. Discovery of the Physiological Roles of Estrogen and Progesterone, E Diczfalusy, I S Fraser. Historical Overview, J W Goldzieher. Drug Regulatory Testing, R a Edgren. Section 2. Chemistry. Structure-Function Relationships and Metabolism of Estrogens and Progestogens, F Z Stanczyk. Chemistry of Antihormones, G C Davies. Chemical Synthesis, J Edwards, M Henzl. Section 3. Physiology. Biosynthesis and Secretion of Ovarian and Adrenal Steroids. S G Hillier. Metabolism of Estrogens and Progestogens, C Longcope. Feedback Mechanisms, D T Baird. The Normal Menstrual Cycle; Changes Throughout Life, R J Norman, G Phillipson. Actions of Estrogens and Progesterone at the Cellular Level, S Christin-Maitre, N Chabbert-Buffet, P Bouchard. The Molecular Basis for the Development of Estrogen and Progesterone Agonists and Antagonists, D P Mcdonnell, B L Wagner. Effects of Estrogen and Progesterone on the Endometrium, H O D Critchley, D L Healy. Menstruation, P a Rogers. Effects of Estrogen and Progesterone on Myometrium, Cervix, Fallopian Tube, Vagina and Vulva, R P S Jansen. Effects of Estrogen and Progesterone on the Breast, W H Hindle. Effects of Estrogen and Progesterone on the Central Nervous System, T Polcz, T Horvath F Naftolin. Effects of Estrogen and Progesterone on Bone, B Winding, H L Jorgensen, C Christiansen. Vascular Effects of Estrogen and Progesterone, V M Miller, G C Sieck, Y Prakash, L a Fitzpatrick. Effects of Estrogen and Progesterone on the Urinary Tract, Rectum and Pelvic Floor, S Johnston, S Stanton. Effects of Estrogen and Progesterone on Skin, M P Brincat, M Formosa. Estrogen and Progesterone During Pregnancy and Parturition, J R G Challis, S J Lye. Estrogens and Progesterone in the Post-Partum Period, P J Illingworth, A S Mcneilly. Estrogens and Progesterone in the Fetus and Neonate, B R Carr, P C Macdonald. Section 4. Pharmacology. Pharmacokinetics of Estrogens and Progestogens, J W Faigle, L Schenkel. Pharmacodynamic Effects of Estrogens and Progestogens, J W Goldzie