Section headings and selected papers: Determining the Biological Environment. Monitoring and control of microbial fermentations, P. M. Salmon & B. C. Buckland. Bioprocess Modeling and Control. Modelling of filamentous microorganisms, J. Nielsen. Bioprocess Identification and Control. Some improvements in the identification of bioprocesses, A. Munack. Data Conditioning and Management. Plant and sensor failure detection by multiple nonlinear filters, R. King. The Future: Artificial Intelligence, Expert Systems and Neural Networks. On-line estimation of bioreactors using recurrent neural networks, S. L. Rivera & M. N. Karim. Modeling, Identification and Control of Biotechnological Processes. Model and control strategies of a two stage anaerobic digestor, J. Alvarez et al . A structured model of Baker's yeast fed-batch growth, P. Dantigny et al . On-line state estimation for L-lysine fermentation, Yung-Chuan Liu et al . Computation of stoichiometric models for bioprocesses, U. Saner et al . A kinetic model of mammalian cell cultures, Xiachang Zhang et al . New Methods: Expert Systems, AI and Neural Network Applications. Knowledge-based planning of mashing profiles, R. J. Aarts. Using neural networks for the interpretation of bioprocess data, G. K. Raju & C. L. Cooney. Debates and Software. The debates, M. N. Pons & M. N. Karim. A program for error diagnosis using a sequential vector comparison test, B. Romein et al . Author index. Keyword index.