Preface.- 1 Introduction to A Handbook of Transcription Factors, Timothy R. Hughes.- 2 An Index of Prokaryotic Transcription Factors, Karthikeyan Sivaraman et al..- 3 A Catalogue of Eukaryotic Transcription Factor Types, their Evolutionary Origin, and Species Distribution, Matthew T. Weirauch and Timothy R. Hughes.- 4 Function and Evolution of C2H2 Zinc Finger Arrays, Lisa Stubbs, Younguk Sun and Derek Caetano-Anolles.- 5 Homeodomain Sybtypes and Functional Diversity, Thomas R. Bürglin.- 6 Nuclar Receptors, Keith Pardee, Aleksander S. Necakov, Henry Krause.- 7 Methods for Analysis of Transcription Factor DNA-binding Specificity in vitro, Arttu Jolma, Jussi Taipale.- 8 Identification of Transcription Factor-DNA Interactions in vivo, Duncan T. Odom.- 9 How Transcription Factors Identify Regulatory Sites in Genomic Sequence, Yair Field, Eilon Sharon, Eran Selgal.- 10 Transcription Factor in Binding Sites and other Features in Human and Drosophila Proximal Promoters, Charles Vinson, Raghunath Chatterjee, Peter Fitzgerald.- 11 Interactions of Transcription Factors with Chromatin, Harm van Bakel.- 12 Transcription Factors Effector Domains, Seth Frietze, Peggy J. Farnham.- 13 Large-scale Nuclear Architecture and Transcriptional Control, Juan M. Vaquerizas, Asifa Akhtar, Nicholas M. Luscombe.- Index