Section I: Introduction, 1. Introduction and innovations in brachytherapy, 2. Standard Technology in Brachytherapy, 3. Radionuclides in Brachytherapy: Current and Potential New Sources, 4. Quality Assurance of Equipment, Section II: Brachytherapy Dosimetry, 5. Source Calibration, 6. Experimental Dosimetry Methods, 7. Computational Methods for Dosimetric Characterization of Brachytherapy Sources, Section III Brachytherapy Treatment Planning and Imaging, 8. Historical Development of Predictive Dosimetry "Systems", 9. TG-43 Dose Calculation Formalism: Development, Insights, and Modernization, 10. On the Introduction of Model-based Algorithms Performing Scatter and Non-Water Heterogeneity Corrections into Brachytherapy Treatment Planning, 11. Optimization and Evaluation, 12. Quality Management of Treatment Planning, 13. Practical use, limitations, and quality control of imaging in Brachytherapy, Section IV: Uncertainties in Clinical Brachytherapy, 14. Uncertainties Associated with Brachytherapy Source Calibrations and Dose Calculations, 15. Uncertainties associated with clinical aspects of brachytherapy, Section V: Clinical Brachytherapy, 16. Clinical use of brachytherapy, 17. Radiobiology for Brachytherapy, 18. Brachytherapy for Prostate Cancer, 19. Gynaecologic Brachytherapy, 20. Brachytherapy for the treatment of breast cancer, 21. Skin brachytherapy including keloids and pterygium, 22. Brachytherapy for Head and Neck Cancers and Uveal Melanoma, 23. Oesophagus, liver and anorectal brachytherapy/ Liver Brachytherapy/Rectal and Anal Cancers, Section VI: Advance Methods and Technologies, 24. In Vivo Dosimetry in Brachytherapy, 25. Electromagnetic tracking, 26. Special Brachytherapy Modalities, 27. Advanced Brachytherapy Technologies: Encapsulation, Ultrasound, and Robotics, Section VII: Radiation Protection and Quality Management in Brachytherapy, 28. Radiation Protection in Brachytherapy, 29. Quality Management in Brachytherapy, 30. Quality Audits in Brachytherapy, 31. Expert Training in Brachytherapy