Preface 7; Henk Hogeveen; Organizing committee 8; Scientific committee 8; Keynotes; Mastitis research and control: Where do we come from and where are we going? 23; K. Larry Smith; Pathogenesis of mastitis and mammary gland immunity: Where we are and where we should go 31; Alfonso Zecconi; Mastitis management in an economic framework 41; Henk Hogeveen and Olav Osteras; New antimicrobial agents in mastitis therapy 53; Stefan Soback and Arthur Saran; The contribution of science to progress in milking technology 58; Graeme Mein; Mastitis in small ruminants 67; A. Contreras, A. Sanchez, J.C. Corrales, D. Sierra, C. Gonzalo and M.J. Paape; Animal welfare: Of increasing importance in modern dairy production 75; Charlotte Hallen Sandgren and Torkel Ekman; Diagnosis of mastitis and indicators of milk quality 82; J. Hamann; Mastitis control systems: The Norwegian experience 91; Olav Osteras and Liv Solverod; Antimicrobial resistance in mastitis organisms as a public health threat 102; Dik Mevius, Otlis Sampimon and Jan Sol; Environmental control for mastitis prevention, milk quality and food safety 109; Ynte H. Schukken, Linda L. Tikofsky and Ruth N. Zadoks. Genetic improvement in mastitis control programmes 115; R.F. Veerkamp and Y. de Haas; Milk production and mastitis control in emerging dairy countries: The experience in Chile 123; Juan Kruze; Pathogenesis and immunology; Pathogenesis of chronic intramammary Escherichia coli infections 131; Belgin Dogan, Suzanne Klaessig, Kenneth Simpson, Steve Oliver, Raul Almeida and Ynte H. Schukken; Persistence of Streptococcus uberis in bovine mammary epithelial cells 137; R.A. Almeida, T. Batcha and S.P. Oliver; Association between genotype of Staphylococcus aureus, recovered at the end of lactation, and cure of the organism in the dry period 143; Randy T. Dingwell, Ken E. Leslie and Parviz Sabour; Toxin genes of Staphylococcus aureus isolated from bovine intramammary infection of different clinical characteristics and outcome 149; Changes in leucocyte surface receptor expression and functional responses in dairy cows with Staphylococcus aureus infection 155; H. Nagahata, H. Higuchi, M. Nakamura, K. Yayou, K. Kawai and A. Ogata; Vitamin E supplementation and udder health: A meta-analysis 159; N. Moyo, M. Nielen, C. Kruitwagen and A.C. Beynen; [alpha]-Tocopherol concentration and stereoisomer composition in plasma and milk from dairy cows fed natural or synthetic vitamin E around calving 166; Guillermo Meglia, Soren K. Jensen, Charlotte Lauridsen and Karin Persson Waller; Comparison of blood and milk non-specific immune parameters in heifers after calving 172; Renata Piccinini, Enrica Binda, Michela Belotti, Giuseppe Casirani and Alfonso Zecconi; Influence of resident milk neutrophils chemiluminescence and viability on the severity of bovine coliform mastitis 178; J. Mehrzad, L. Duchateau and C. Burvenich. Potential association of polymorphisms in the bovine CXCR2 gene with neutrophil survival and killing ability 185; Gina M. Pighetti and Magdalena Rambeaud; Differential cell count and interdependence of udder quarters 190; J. Hamann, A Schroder and R. Merle; Response of rhlf-transgenic dairy cows to expermentally induced escherichia coli mastitis 196; Paula Hyvonen, Leena Suojala, Toomas Orro, and Satu Pyorala; Cell function in the bovine mammary gland: Interdependence of healthy and infected udder quarters 202; R. Merle, A. Schroder and J. Hamann; Delayed neutrophil apoptosis in bovine subclinical mastitis: Possible involvement in persistent accumulation of cells in milk 208; P. Boutet, L. Gillet, R. Closset, A. Vanderplasschen, F. Bureau and P. Lekeux; Economics of mastitis and mastitis management; Use of partial budgeting to determine the economic benefits of antibiotic treatment during lactation of chronic subclinical mastitis caused by Staphylococcus aureus 217; J.M. Swinkels, R.N. Zadoks and H. Hogeveen; Impact of epidemiological, zootechnical, managerial and price factors on the economic efficacy of subclinical mastitis treatment during lactation 224; Francis Serieys; Stochastic economic modeling of the use of penethamate hydriodide (Mamyzin[registered]) in heifers around calving to control peri-parturient mastitis 232; Mark A. Bryan and Gabriele M. Friton; Importance of uncertainties in the effects of pathogen specific mastitis on profit in dairy herds estimated by stochastic simulation 235; Soren Ostergaard, Mizeck G. G. Chagunda, Torben W. Bennedsgaard, Nicolas C. Friggens and Jens Y. Blom; Costs and benefits of improved milking practices in smallholder dairy farms in the 10th region of Chile 242; G. van Schaik, L.E. Green, D. Guzman, H. Esparza and N. Tadich. Udder health, treatments and pathogens in organic dairy herds in the Netherlands 248; E.A.A. Smolders, J. van der Werf, D. van de Mortel and A. Kijlstra; High milk yields and the risk of mastitis in different herd environments 254; Jack J. Windig, Mario P.L. Calus and Roel F. Veerkamp; Association between somatic cell count in early lactation and culling of dairy heifers using Cox frailty models 260; Sarne De Vliegher, Herman W. Barkema, Geert Opsomer, Aart de Kruif and Luc Duchateau; Therapy and immunization; Reducing subclinical and clinical mastitis in dairy heifers by precalving infusion of a teat sealant and/or parenteral antibiotic therapy 269; Scott McDougall, Katrina Parker, Chris Compton and Cord Heuer; Chemotherapeutic approaches to bovine mastitis caused by Staphylococcus aureus through strain identification using random amplified polymorphic DNA analysis 274; S.R. Sebastian, K. Vijayakumar and P. Ramadass; Efficacy of a cloxacillin dry cow product for treatment of heifers on farms with a low and a high prevalence of heifer mastitis in The Netherlands 278; Otlis Sampimon and Jan Sol; Efficacy of a J-5 Escherichia coli bacterin in clinical coliform mastitis of dairy cattle 285; Hubert A. Deluyker, Karen Van Uffel, Gregory D. Elfring, Sophie N. Van Oye, Christopher Dutton and Ian Nanhjiani; Effect of carprofen following experimentally induced E. coli mastitis in primiparous cows 290; F. Vangroenweghe, P. Boutet, P. Lekeux, R. Bossuyt, P. Rainard, M.J. Paape, L. Duchateau and C. Burvenich; Iron uptake and growth responses by Escherichia coli cultured with antibodies from cows immunized with high affinity ferric receptors 297; J.S. Hogan, K.L. Smith, J. Lin, K. Takemura and S.L. Wolf; In vitro susceptibility of biofilm growing Staphylococcus aureus isolates for 10 antibiotics 302; Marielle B. Melchior, Johanna Fink-Gremmels and Wim Gaastra. Better management of mastitis treatment: Contribution of consensus conference methodology 307; Jacqueline Bastien, Chantal Legrand, Pierre Brouillet, Natalie Durnford and Gerard Bosquet; Leukocyte dynamics and cytokine expression in response to mycobacterial water soluble compounds in bovine mastitis 314; Reena Mukherjee; Direct and indirect effects of subclinical mastitis treatment in dairy herds 321; John Barlow, Cameron Nightingale, Ruth Zadoks, Lisa White and Ynte Schukken; Therapeutic treatment with casein hydrolyzate eradicate effectively bacterial infection in treated mammary quarters in cows 327; Nissim Silanikove, Jose Iscovich and Gabriel Leitner; Antibiotic resistance in Staphylococcus aureus isolated from bovine udders: Development related to introduction of dry cow therapy? 333; Anne Cathrine Whist; Orbeseal[registered] and Orbenin[registered] EDC in combination for the treatment of intra-mammary infections at drying off and prevention of new infections during the dry period and early lactation in dairy cows 339; Andrew Bradley, Hamish Newton, Hafid Benchaoui, Nicola Tilt, Vic Cracknell and Tim Rowan; The safety and efficacy of the immunotherapy treatment Y-Complex in a clinical mastitis study under field conditions 345; Y. Pinchasov, J. Spanier, G. Lietner, J. Pitcovsky, E. Morag, D. Raymond and A. Gordon; Therapeutic effect of systemic or intra-mammary antibiotic treatment of bovine sub-clinical mastitis during lactation 351; Charlotte Hallen Sandgren, Karin Persson Waller and Ulf Emanuelson; An alternative treatment trial for Staphylococcus aureus mastitis in organically managed dairy cattle 358; L.L. Tikofsky and R.N. Zadoks; Prepartum intramammary antibiotic therapy: Effects on udder health, milk production, and reproductive performance in dairy heifers 364; A.A. Borm, L.K. Fox, K.E. Leslie, J.S. Hogan, S.M. Andrew, S.P. Oliver, Y.H. Schukken, D.D. Hancock C.T. Gaskins, W.E. Owens and C. Norman. Milking technology; Milking machine test survey 373; Elizabeth A. Berry, J. Eric Hillerton and Mark Scrivens; Machine milking risk factors for teat end callosity in dairy cows on herd level 376; F. Neijenhuis G.H. Klungel H. Hogeveen and J.P.T.M. Noordhuizen; Long-term effects of different pulsation characteristics on teat thickness, teat skin moisture and teat skin pH of dairy cows 383; Stefanie Hansen and Jorn Hamann; Details of some of the forces applied to the cow's teat during milking 390; D. Boast, M. Bennett, M. Hale, D.M. Turner, J. Allcock and J.E. Hillerton; Effects of lactic acid teat dip on chapped teat skin 397; E. Izak, J.P. Araya and L.C. Perren; Technical success and effectiveness of teat cleaning in automatic milking in Finland 401; M. Hovinen, A-M. Aisla and S. Pyorala; Diagnosis of mastitis and indicators for milk quality; Use and interpretation of bacteriology in the diagnosis of bovine intramammary infection 409; A.J. Bradley, H. Newton and M.J. Green; Evaluation of the Petrifilm[trademark] culture system for the identification of mastitis bacteria as compared to standard bacteriological methods 416; Ken Leslie, Matt Walker, Erin Vernooy, Anna Bashiri and Randy Dingwell; Testing for Staphylococcus aureus in herds with a low bulk milk somatic cell count 422; T.J.G.M Lam and Y.H. Schukken; Simultaneous detection of mastitis pathogens in milk by multiplex real-time polymerase chain reaction 427; B.E. Gillespie and S.P. Oliver; Optimised sample sizes for analysing the genetic heterogeneity of mammary pathogen isolates from environmental samples 434; D. Dopfer, R.N. Zadoks, W. Buist and B. Engel. Somatic cell count patterns to improve udder health by genetics and management 439; Yvette de Haas, Herman W. Barkema, Ynte-Hein Schukken, Gerben de Jong and Roel F. Veerkamp; Changes in lactate dehydrogenase, N-acetyl-[beta]-D-glucosaminase, and somatic cell count in relation to development of mastitis in dairy cows 445; M.G.G. Chagunda, T. Larsen, M. Bjerring and K.L. Ingvartsen; Prevalence of contagious mastitis pathogens in bulk tank milk from Prince Edward Island dairy farms 449; Richard G.M. Olde Riekerink, Herman W. Barkema, Stefan Veenstra, Henrik Stryhn, Doris E. Poole, Randy T. Dingwell and Greg P. Keefe; A Bayesian approach to interpreting Staphylococcus aureus diagnostic indicators for on-farm decision making 455; Sandra Costello, George Shook and Terry Smith; Variation in somatic cell count and milk components in fraction collected quarter milk samples 462; Liv Solverod, Sigrid Simonsen, Andres Waldmann, Olav Osteras, Erik Ropstad; Using milk L (+) lactate as a diagnostic tool to detect bovine mastitis in the early lactation 467; N.Th. Grabowski, R. Redetzky, A. Sulzer, J. Hamann and G. Klein; Milk amyloid A (MAA) concentration and somatic cell count (SCC) in the diagnosis of bovine mastitis 473; H.H. Petersen, I.A. Gardner, P. Rossitto, H.D. Larsen and P.M.H. Heegaard; Diagnosis of mastitis by benzoic acid (benzene sulfonic acid) and sodium carbonate on pregnant and lactating mastitic animals 477; M. Mazhar Ayaz and Masood Akhtar; Use of on-farm testing of somatic cell count for selection of udder quarters for bacteriological culturing 481; Tine van Werven, Cindy Nijhof, Twan van Bussel and Henk Hogeveen; Diagnostic value of the California Mastitis Test in comparison to electronically-counted somatic cells in bovine milk 487; R. Redetzky, J. Hamann, N.Th. Grabowski and G. Klein. Mastitis in small ruminants; Aetiological, clinical and epidemiological characterization of clinical mastitis in dairy sheep 497; Dominique Bergonier, Gilles Lagriffoul, Francis Barillet, Rachel Rupp, Aurele Valognes, Roland Brugidoux, Regis Duquesnel and Xavier Berthelot; Detection of enterotoxins and virulence genes in Staphylococcus aureus strains isolated from sheep with subclinical mastitis 504; E. De Santis, A. Mureddu, R. Mazzette, C. Scarano and M. Bes; Subclinical mastitis affects the plasmin system, milk composition and curd yield in sheep and goats: comparative aspects 511; Nissim Silanikove, Fira Shapiro, Gabriel Leitner and Uzi Merin; Host response reactions of the lactating ovine udder during experimental challenge with Staphylococcus epidermidis 517; Petra Winter, Klemens Fuchs, Franz Schilcher and Ian G. Colditz; Efficacy of antibiotic treatment at drying-off in curing existing infections and preventing new infections in dairy goats 523; Scott McDougall and Fiona Anniss; Animal welfare issues related to mastitis; Associations between hygiene scores and udder health parameters in organic dairy herds 531; Ilka C. Klaas, Torben W. Bennedsgaard and Mette Vaarst; Teat lesions and teat necrosis in heifers in The Netherlands 537; Jan Sol, Gerard Wellenberg, Otlis Sampimon, Joost Snoep, Hans Miltenburg and Petra Kock; Effect of stockperson-dairy cow interaction to mammary gland health 544; Claudia R. Valle, Andrea R. Ribeiro, Flavio A. Braga, Matheus J.R. Paranhos da Costa, Marcelo S. Rosa and Andre S.C. Dias; Control programmes; The systems approach to udder health control 551; J.P.T.M. Noordhuizen and H. Hogeveen. The importance of a low SCC premium policy in the reduction of population wide SCC levels 558; Cameron Nightingale and Ynte Schukken; Use of SCC in genetic selection for reduced incidence of mastitis: A mixture model approach 564; J. Odegard, P. Madsen, D. Gianola, G. Klemetsdal, J. Jensen, B. Heringstad and I.R. Korsgaard; Genetic improvement of mastitis resistance in Norwegian Red (NRF) 570; Bjorg Heringstad, Yu-Mei Chang, Daniel Gianola and Gunnar Klemetsdal; Social factors related to mastitis control practices: The role of dairy farmers' knowledge, attitude, values, behaviour and networks 576; D. Kuiper, J. Jansen, R.J. Renes, C. Leeuwis and H. van der Zwaag; Mastitis and farmers perceptions and actions: An anthropological perspective to the phenomenon of mastitis 583; M. Vaarst; Implementation of recommended mastitis prevention management practices and the herd level prevalence of contagious mastitis pathogens on Canadian dairy farms 587; Richard G.M. Olde Riekerink, Herman W. Barkema, Daniel T. Scholl, David F. Kelton and Greg P. Keefe; A national research network to promote mastitis control in Canada 593; D. Scholl, G. Tomita, S. Messier, H. Barkema, P. Lacasse, X. Zhao and E. Bouchard; Mastitis control program in The Netherlands: Goal, tools and conditions 599; H.G. van der Zwaag, G. van Schaik and T.J.G.M. Lam; "FRISKKO - JUVER" ("Healthycow - Udder") A systematic veterinary approach to udder disease in dairy herds 605; Torkel Ekman, Hakan Landin, Johan Waldner, Mats Gyllensward and Charlotte Hallen Sandgren; Monitoring daily measurements of somatic cell count: Automatic and on-line detection of mastitis 611; I.R. Korsgaard, P. Lovendahl and K.H. Sloth; A biological model for detecting individual cow mastitis risk based on lactate dehydrogenase 617; Mizeck G.G. Chagunda, Nicolas C. Friggens and Morten D. Rasmussen. Risk of clinical mastitis within lactation in Dutch dairy cattle 622; Gustavo Monti and Gerben De Jong; Environmental control; Feeding factors associated with clinical mastitis of first parity cows 629; Ann-Kristin Arvidson, Torkel Ekman, Ulf Emanuelson, Anders H. Gustavsson, Charlotte Hallen Sandgren, Kjell Holtenius, Karin Persson Waller and Catarina Svensson; Isolation of Streptococcus uberis from different sites of the dairy cow 635; S.J. Lacy-Hulbert, R.T. Cursons, M.G. Lopez-Benavides, J.H. Williamson, E.L. Summers, S.M. Pryor and M.W. Woolford; Risk factors contributing to udder health depression during alpine summer pasturing in Swiss dairy herds 642; M. Walkenhorst, J. Spranger, P. Klocke and W. Scharen; Streptococcus uberis population dynamics in the New Zealand pastoral dairy farm 649; M.G. Lopez-Benavides, J.H. Williamson, R.T. Cursons, S.J. Lacy-Hulbert and M.W. Woolford; A methodology to quantitatively identify effective measures to control environmental mastitis 656; Marc Vissers, Meike te Giffel, Frank Driehuis, Peter de Jong and Jos Lankveld; Food safety issues related to mastitis; On-Farm sources of foodborne pathogens: Isolation from the dairy farm environment 665; S.P. Oliver, S.E. Murinda, L.T. Nguyen, H.M. Nam, R.A. Almeida and S.J. Headrick; Shiga Toxin Genes from Escherichia coli strains isolated from mastitic milk 671; Ray T. Cursons, J. Williamson and A. Bean; Influences on excretion of antibiotic residues in milk with special emphasis on milking frequency 677; Karin Knappstein, Gertraud Suhren, Hans-Georg Walte; Antimicrobial susceptibility of Staphylococcus spp. isolated at dry-off and calving 684; P.J. Rajala-Schultz, A. Torres, S. Rajeev, F.J. DeGraves and F. Silveira. Prepartum intramammary antibiotic therapy: Effect on risk of antibiotic residues in milk from dairy heifers 688; K.J. Steinman, S.M. Andrew, A.A. Borm, L.K. Fox, K.E. Leslie, J.S. Hogan, S.P. Oliver, Y.H. Schukken, W.E. Owens and C. Norman; Mastitis control in emerging dairy countries; Role of selective dry cow therapy in prevention of mastitis in dairy herds with high disease prevalence 697; B.K. Bansal, P.S. Dhaliwal, N.S. Bajwa and S.S. Randhawa; Mastitis control in Uruguay: Strengths and weaknesses 703; M. Bouman, R. Bianco, E. Gianneechini, D. Hirigoyen and E. De Torres; The impact of intervention on mastitis in an emerging dairy developing country-Uganda 709; D.K. Byarugaba, J.L. Nakavuma, C. Laker and M. Vaarst; Environmental factors affecting somatic cells counts in milk from small dairies in Southern Brazil 716; G. Noro, J.W. Durr, F.H.D. Gonzalez and R. Campos; Risk indicators associated with Staphylococcus aureus subclinical mastitis in smallholder dairy cows in Tanzania 722; F.M. Kivaria, J.P.T.M. Noordhuizen and A.M. Kapaga; Subclinical mastitis in buffaloes in different herd sizes and milking management systems 728; Chirathalattu Santosh Thomas, Helena Nimmervoll, Caroline Boije, Kerstin Svennersten-Sjaunja, Nils Lundeheim and Karin Ostensson.