Part 1 The foundation for advanced practice nursing: advanced practice nursing at the dawn of the 21st century - practice, education and research, Joanne V. Hickey; education for advanced practice nursing, Catherine L. Gilliss; professional development -socializtion in advanced practice nursing, M. Elizabeth Hixon; practice credentials - licensure, approval to practice, certification and privileging, Carolyn K. Lewis and Mary C. Smolenski; clinical reasoning, Nancy L. Szaflarski; case presentations. Part 2 Changing environments and patient diversity in health care delivery: healthcare delivery systems and environments of care, Sandra L. Venegoni; the renaissance of primary care - an opportunity for nursing, Jean Goeppinger and Rosalie Hammond; the advanced practice nurse in a managed care environment, Marjorie A. Satinsky; advanced practice nursing in the postacute continuum for the older person, Mary Pat Rapp; nursing informatics, Carol A. Romano; diversity - a call for culturally competent practitioners, Angeline Bushy; alternative and complementary therapies, Joan Engebretson. Part 3 Practice and economic imperatives in advanced practice nursing: accountability - the covenant between patient and advanced practice nurse, Neville E. Strumpf et al; political activism - moving the profession forward, JoAnne Kirk Henry; the research basis for practice - the foundation of evidence-based practice, Vicki L. Kraus; economics and healthcare financing, Peter I. Buerhaus. Part 4 The advanced practice nurse - role and innovative models for caring: primary care - improving health promotion and disease prevention - exemplars; management of high-risk and vulnerable populations - exemplars; pushing the boundaries of advanced practice nursing - exemplars.