Diagnostic Molecular Pathology

This is the first manual to target the pathologist specifically. These two volumes bring together a broad spectrum of protocols relevant to the routine molecular analysis of pathological samples, written at a level which assumes little previous knowledge of the subject as many people working in clinical pathology laboratories have only limited experience of molecular techniques. Topics in Volume I include those methods which relate to morphological analysis, such as immunocytochemistry, in situ hybridization, chromosome analysis, and flow cytometry. Volume II demonstrates additional applications of molecular techniques to clinical samples, including the use of PCR, DNA sequencing, and nucleic acid hybridization for such diverse purposes as pathogen identification and forensic studies. Expert guidance and detailed instruction on how to ensure accuracy and reliability for all the protocols is provided. This book is intended for pathologists, medical scientists, post-graduate students.